Substrate: Notch2 (Cell surface receptor)
Seq-ID: O35516 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor activity,
calcium ion binding,
protein binding		 integral to plasma membrane,
cell surface,
nucleus		 morphogenesis of an epithelial sheet,
transcription,
negative regulation of cell proliferation,
cell cycle arrest,
cell growth,
positive regulation of Ras protein signal transduction,
regulation of transcription,
positive regulation of apoptosis,
Notch signaling pathway,
determination of left/right symmetry,
regulation of developmental process,
cell fate determination,
embryonic limb morphogenesis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 1777 KAKAEDEALLSEDDPIDRRPW - 19144319
HTP
0.39
 - -
0.65
 - medium
S 1840 LMLASLRGGSSDLSDEDEDAE - 19144319
HTP
0.12
 - ANK
0.71
 - medium
S 1843 ASLRGGSSDLSDEDEDAEDSS - 19144319
HTP
0.02
 - ANK
0.77
 - medium
T 2066 IVRLLDEYNVTPSPPGTVLTS GSK-3_beta 12794074
LTP
0.00
 MOD_GSK3_1
 - -
0.47
 - medium
S 2068 RLLDEYNVTPSPPGTVLTSAL GSK-3_beta 12794074
LTP
1.00
 MOD_GSK3_1
 - -
0.49
 - medium
T 2072 EYNVTPSPPGTVLTSALSPVL GSK-3_beta 12794074
LTP
0.08
 MOD_GSK3_1
 - -
0.52
 - medium
S 2091 VLCGPNRSFLSLKHTPMGKKA GSK-3_beta 12794074
LTP
0.25
 MOD_GSK3_1
 - -
0.55
 - medium

Substrate: Notch2 (Cell surface receptor)
Seq-ID: Q04721 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-61989   SMAD1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor activity,
calcium ion binding,
ligand-regulated transcription factor activity,
protein binding		 integral to plasma membrane,
cell surface,
nucleus		 nervous system development,
transcription,
negative regulation of cell proliferation,
anti-apoptosis,
cell cycle arrest,
cell growth,
positive regulation of Ras protein signal transduction,
hemopoiesis,
stem cell maintenance,
Notch signaling pathway,
regulation of transcription, DNA-dependent,
cell fate determination,
induction of apoptosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 1716 HGSLWLPEGFTLRRDASNHKR - 18669648
HTP
0.00
 - -
0.42
 - medium
S 1778 KVKAEDEALLSEEDDPIDRRP - 18669648
HTP
0.44
 - -
0.64
 - medium
T 1802 QHLEAADIRRTPSLALTPPQA - 18669648
HTP
0.12
 - -
0.72
 - medium
S 1804 LEAADIRRTPSLALTPPQAEQ - 18669648
HTP
0.23
 - -
0.73
 - medium
T 1808 DIRRTPSLALTPPQAEQEVDV - 15302935
HTP
1.00
 - -
0.71
 - medium
T 1808 DIRRTPSLALTPPQAEQEVDV - 18669648
HTP
1.00
 - -
0.71
 - medium
S 1841 PLMLASLRGGSSDLSDEDEDA - 18669648
HTP
0.06
 - ANK
0.67
 - medium
S 1845 ASLRGGSSDLSDEDEDAEDSS - 18669648
HTP
0.02
 - ANK
0.76
 - medium
S 2070 RLLDEYNVTPSPPGTVLTSAL - 15302935
HTP
1.00
 - -
0.49
 - medium
S 2070 RLLDEYNVTPSPPGTVLTSAL - 18669648
HTP
1.00
 - -
0.49
 - medium
T 2074 EYNVTPSPPGTVLTSALSPVI - 18669648
HTP
0.07
 - -
0.52
 - medium
S 2081 PPGTVLTSALSPVICGPNRSF - 18669648
HTP
0.29
 - -
0.46
 - medium
T 2097 PNRSFLSLKHTPMGKKSRRPS - 18669648
HTP
0.16
 - -
0.70
 - medium
T 2296 SRPPEGKHITTPREPLPPIVT - 18669648
HTP
0.01
 - -
0.79
 - medium

Substrate: Notch2 (Cell surface receptor)
Seq-ID: Q9QW30 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor activity,
calcium ion binding,
protein binding		 integral to plasma membrane,
cell surface,
nucleus		 transcription,
negative regulation of cell proliferation,
cell cycle arrest,
cell growth,
positive regulation of Ras protein signal transduction,
regulation of transcription,
tissue regeneration,
Notch signaling pathway,
regulation of developmental process,
cell fate determination
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 2078 TPSPPGTVLTSALSPVLCGPN - 11577080
LTP
0.25
 - -
0.54
 - medium

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