Substrate: NPM (nucleophosmin (nucleolar phosphoprotein B23) (from PhosphoBase))
Seq-ID: Q61937 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-68675   RS27_MOUSE
MINT-68676   YBOX1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
rRNA binding,
DNA binding,
unfolded protein binding,
NF-kappaB binding		 granular component,
cytosol,
large ribosomal subunit,
small ribosomal subunit,
nuclear speck		 ribosomal large subunit biogenesis,
positive regulation of cell proliferation,
positive regulation of protein kinase activity,
cell volume homeostasis,
ribosomal small subunit biogenesis,
negative regulation of cell proliferation,
cell growth,
positive regulation of centrosome duplication,
cell aging,
regulation of DNA damage response, signal transduction by p53 class mediator,
centrosome cycle,
rRNA export from nucleus,
ribosomal small subunit export from nucleus,
negative regulation of nuclear mRNA splicing, via spliceosome,
ribosomal large subunit export from nucleus,
protein localization
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 70 VEAEAMNYEGSPIKVTLATLK - 19144319
HTP
0.92
 - Nucleoplasmin
0.42
 --
S 125 HLVAVEEDAESEDEDEEDVKL - 16452087
HTP
1.00
 - Nucleoplasmin
0.79
 --
S 258 KMQASIEKGGSLPKVEAKFIN - 17203969
HTP
0.96
 - -
0.57
 --

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