Phospho.ELM Result

a database of S/T/Y phosphorylation sites

ITCH (protein binding, ubiquitin-protein ligase activity)

Seq-ID:

Q8C863 [Mus musculus]

Download:

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

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Molecular Function	Cellular Component	Biological Process
protein binding, ubiquitin-protein ligase activity	plasma membrane, membrane fraction, cytoplasmic vesicle, nucleus, cell cortex	positive regulation of protein catabolic process, negative regulation of apoptosis, apoptosis, positive regulation of T cell anergy, negative regulation of alpha-beta T cell proliferation, negative regulation of defense response to virus, innate immune response, protein K48-linked ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, protein K63-linked ubiquitination, protein K29-linked ubiquitination, protein polyubiquitination, response to virus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	199	GENKRANGNNSPSLSNGGFKP	MAPK8	16446428	LTP	0.40	MOD_ProDKin_1	-	-	0.88	-	medium
T	222	PPRPSRPPPPTPRRPASVNGS	MAPK8	16446428	LTP	0.50	MOD_ProDKin_1	-	-	0.98	-	medium
S	232	TPRRPASVNGSPSTNSDSDGS	MAPK8	16446428	LTP	0.39	MOD_ProDKin_1	-	-	0.96	-	medium