List of substrates found:

FCER1G  MS4A2  Bcr  P130Cas 


Substrate: FCER1G (FceRI gamma)
Seq-ID: P30273 [Homo sapiens]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
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Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 65 ITSYEKSDGVYTGLSTRNQET - 18088087
HTP
1.00
FES SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.29
- low
Y 65 ITSYEKSDGVYTGLSTRNQET - 18083107
HTP
1.00
FES SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.29
- low
Y 76 TGLSTRNQETYETLKHEKPPQ - 18088087
HTP
1.00
FES SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.54
- low
Y 76 TGLSTRNQETYETLKHEKPPQ - 18083107
HTP
1.00
FES SH2;
SHC1 SH2;
SYK SH2;
ZAP70 SH2
ITAM
0.54
- low

Substrate: MS4A2 (calcium channel activity)
Seq-ID: Q01362 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 219 KGNKVPEDRVYEELNIYSATY - 15339926
LTP
0.12
FES SH2;
Lyn SH2;
SHC1 SH2;
SYK SH2
-
0.21
- medium

Substrate: Bcr (Breakpoint cluster region protein)
Seq-ID: P11274 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 177 QPGADAEKPFYVNVEFHHERG Fes 8955135
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG Fes 10405761
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG - 12522270
HTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG - 9178913
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG - 12124177
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG - 9407116
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG Abl 16912036
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG HCK 16912036
LTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium
Y 177 QPGADAEKPFYVNVEFHHERG - 18083107
HTP
0.75
ABL1 SH2;
FES SH2;
GRAP SH2;
GRB2 SH2;
PTPN11 SH2
-
0.68
- medium

Substrate: P130Cas (Adaptor molecule. Contain 15 YxxP motifs. )
Seq-ID: P56945 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 664 ENSEGGWMEDYDYVHLQGKEE - 8621540
LTP
1.00
FES SH2;
Fyn SH2;
Lck SH2;
Src SH2
-
0.49
- medium
Y 664 ENSEGGWMEDYDYVHLQGKEE - 11604500
LTP
1.00
FES SH2;
Fyn SH2;
Lck SH2;
Src SH2
-
0.49
- medium


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