a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	SYK (Spleen tyrosine kinase )
Seq-ID:	P43405 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-56730   LCK_HUMAN MINT-56732   P85A_HUMAN MINT-56739   FGR_HUMAN MINT-56749   P85B_HUMAN MINT-74763   EGFR_HUMAN MINT-74769   ERBB2_HUMAN MINT-74775   ERBB3_HUMAN MINT-74776   ERBB4_HUMAN MINT-6538977   CBL_HUMAN MINT-6621148   BLNK_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process non-membrane spanning protein tyrosine kinase activity, ATP binding, integrin binding cytoplasm, T cell receptor complex protein complex assembly, organ morphogenesis, integrin-mediated signaling pathway, neutrophil chemotaxis, interspecies interaction between organisms, cell proliferation, leukocyte cell-cell adhesion
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	348	REALPMDTEVYESPYADPEEI	SYK	8657103	LTP	0.93		FGR SH2; Lck SH2; PLCG1 SH2; VAV1 SH2	-	0.59	-	-
Y	348	REALPMDTEVYESPYADPEEI	-	12522270	HTP	0.93		FGR SH2; Lck SH2; PLCG1 SH2; VAV1 SH2	-	0.59	-	-
Y	348	REALPMDTEVYESPYADPEEI	-	18083107	HTP	0.93		FGR SH2; Lck SH2; PLCG1 SH2; VAV1 SH2	-	0.59	-	-
Y	352	PMDTEVYESPYADPEEIRPKE	SYK	8657103	LTP	1.00		FGR SH2; Lck SH2; PLCG1 SH2; VAV1 SH2	-	0.53	-	-
Y	352	PMDTEVYESPYADPEEIRPKE	-	12522270	HTP	1.00		FGR SH2; Lck SH2; PLCG1 SH2; VAV1 SH2	-	0.53	-	-
Y	352	PMDTEVYESPYADPEEIRPKE	-	18083107	HTP	1.00		FGR SH2; Lck SH2; PLCG1 SH2; VAV1 SH2	-	0.53	-	-

Substrate:	CD150 (T cell antigen receptor)
Seq-ID:	Q13291 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process antigen binding, transmembrane receptor activity integral to membrane positive regulation of cell proliferation, lymphocyte activation, interspecies interaction between organisms
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	281	TTVEKKSLTIYAQVQKPGPLQ	Fyn	11806999	LTP	1.00		FGR SH2; INPP5D SH2; PTPN11 SH2; SH2D1A SH2; SH2D1B SH2	-	0.39	-	low
Y	281	TTVEKKSLTIYAQVQKPGPLQ	-	18083107	HTP	1.00		FGR SH2; INPP5D SH2; PTPN11 SH2; SH2D1A SH2; SH2D1B SH2	-	0.39	-	low
Y	327	SVQETNSITVYASVTLPES	Fyn	11806999	LTP	1.00		FGR SH2; INPP5D SH2; PTPN11 SH2; SH2D1A SH2; SH2D1B SH2	-	0.38	-	low
Y	327	SVQETNSITVYASVTLPES	Lyn	15315965	LTP	1.00		FGR SH2; INPP5D SH2; PTPN11 SH2; SH2D1A SH2; SH2D1B SH2	-	0.38	-	low