List of substrates found:

CD28  CSFR-1  Shc  LAT 


Substrate: CD28 (Involved in T cell activation)
Seq-ID: P10747 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 191 SKRSRLLHSDYMNMTPRRPGP Lck 8992971
LTP
0.95
GRAP2 SH2;
GRB2 SH2;
ITK SH2;
PIK3R1 SH2
-
0.44
- medium
Y 191 SKRSRLLHSDYMNMTPRRPGP ITK 8992971
LTP
0.95
GRAP2 SH2;
GRB2 SH2;
ITK SH2;
PIK3R1 SH2
-
0.44
- medium
Y 191 SKRSRLLHSDYMNMTPRRPGP - 16094384
HTP
0.95
GRAP2 SH2;
GRB2 SH2;
ITK SH2;
PIK3R1 SH2
-
0.44
- medium

Substrate: CSFR-1 (Macrophage colony stimulating factor I receptor)
Seq-ID: P07333 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 699 PGQDPEGGVDYKNIHLEKKYV - N.N.
LTP
1.00
GRAP2 SH2;
GRB2 SH2
TyrKc
0.45
- low

Substrate: Shc ( Adaptor molecule)
Seq-ID: P29353 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 349 EEEEEPPDHQYYNDFPGKEPP - 11075717
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP - 9121430
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP SYK 9710204
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP ZAP70 9710204
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP - 10891441
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP - 11687594
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP - 15592455
HTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 349 EEEEEPPDHQYYNDFPGKEPP FLT4 9927207
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 11075717
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR SYK 9710204
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR ZAP70 9710204
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 8610109
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 9741627
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 12522270
HTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 15592455
HTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR FLT4 9927207
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 18083107
HTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--
Y 427 PGRELFDDPSYVNVQNLDKAR - 18669648
HTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--

Substrate: LAT (Adaptor molecule involved in the TCR signal pathway)
Seq-ID: O43561 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 220 AEASLDGSREYVNVSQELHPG - 15659558
HTP
1.00
GRAP2 SH2;
GRB2 SH2;
PIK3R1 SH2;
PLCG1 SH2;
VAV1 SH2
-
0.71
- medium

Substrate: LAT (Adaptor molecule involved in the TCR signal pathway)
Seq-ID: O54957 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 175 SAFSVESCEDYVNVPESEESA - 10811803
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
VAV_group SH2
-
0.71
- low
Y 175 SAFSVESCEDYVNVPESEESA ZAP70 11368773
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
VAV_group SH2
-
0.71
- low
Y 195 AEASLDGSREYVNVSPEQQPV - 10811803
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
VAV_group SH2
-
0.83
- low
Y 195 AEASLDGSREYVNVSPEQQPV ZAP70 11368773
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
VAV_group SH2
-
0.83
- low


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