a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	cdc25c (M-phase inducer phosphatase 3)
Seq-ID:	P30307 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-16690   PLK1_HUMAN MINT-3294433   1433Z_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein tyrosine phosphatase activity, WW domain binding cytosol, nucleoplasm regulation of cyclin-dependent protein kinase activity, cell division, traversing start control point of mitotic cell cycle, protein amino acid dephosphorylation, regulation of mitosis, mitosis, interspecies interaction between organisms, DNA replication, cell proliferation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	130	KCSPAQLLCSTPNGLDRGHRK	CDK1	8119945	LTP	0.20		PLK1 PBD	M-inducer_phosp	0.55	-	low

Substrate:	WEE 1 tyrosine kinase (Dual specificity kinase)
Seq-ID:	P30291 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-50988   1433B_HUMAN MINT-3295375   1433Z_HUMAN MINT-3975741   1433S_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process magnesium ion binding, protein serine/threonine kinase activity, non-membrane spanning protein tyrosine kinase activity, ATP binding, protein binding nucleoplasm protein amino acid phosphorylation, cell division, mitosis
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	53	EGSGHSTGEDSAFQEPDSPLP	PLK1	15070733	LTP	0.36	MOD_PLK	PLK1 PBD	-	0.96	-	medium
S	53	EGSGHSTGEDSAFQEPDSPLP	PLK1	16085715	LTP	0.36	MOD_PLK	PLK1 PBD	-	0.96	-	medium

Substrate:	CHK2 (Serine/threonine-protein kinase Chk2)
Seq-ID:	O96017 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-13742   P53_HUMAN MINT-15591   MPIP1_HUMAN MINT-49652   NBN_HUMAN MINT-58599   MDM2_HUMAN MINT-62311   IMA2_HUMAN MINT-4793727   RB_HUMAN MINT-6806274   STRAP_HUMAN MINT-7294980   XRCC1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein serine/threonine kinase activity, metal ion binding, ATP binding, protein binding PML body protein amino acid phosphorylation, senescence, cell cycle, DNA damage checkpoint, DNA damage response, signal transduction resulting in induction of apoptosis
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	68	GTLSSLETVSTQELYSIPEDQ	ATM	10973490	LTP	0.08	MOD_PIKK_1	MDC1 FHA; PLK1 PBD	-	0.61	-	-
T	68	GTLSSLETVSTQELYSIPEDQ	CHK2	11901158	LTP	0.08	MOD_PIKK_1	MDC1 FHA; PLK1 PBD	-	0.61	-	-
T	68	GTLSSLETVSTQELYSIPEDQ	PLK1	12493754	LTP	0.08	MOD_PIKK_1	MDC1 FHA; PLK1 PBD	-	0.61	-	-
T	68	GTLSSLETVSTQELYSIPEDQ	TTK	15618221	LTP	0.08	MOD_PIKK_1	MDC1 FHA; PLK1 PBD	-	0.61	-	-