List of substrates found:

JAK3  Insulin R  RET  JAK2 


Substrate: JAK3 (Cytoplasmic tyrosine kinase)
Seq-ID: P52333 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 785 RDLNSLISSDYELLSDPTPGA - 15592455
HTP
1.00
SH2B1 SH2 -
0.28
--
Y 785 RDLNSLISSDYELLSDPTPGA JAK3 15121872
LTP
1.00
SH2B1 SH2 -
0.28
--

Substrate: Insulin R (Receptor tyrosine kinase)
Seq-ID: P06213 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1185 IGDFGMTRDIYETDYYRKGGK INSR 7806540
LTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 100.87%
Y 1185 IGDFGMTRDIYETDYYRKGGK - 18083107
HTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 100.87%
Y 1189 GMTRDIYETDYYRKGGKGLLP INSR 7806540
LTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 67.69%
Y 1189 GMTRDIYETDYYRKGGKGLLP - 9506989
LTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 67.69%
Y 1189 GMTRDIYETDYYRKGGKGLLP - 18083107
HTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 67.69%
Y 1190 MTRDIYETDYYRKGGKGLLPV INSR 7806540
LTP
1.00
GRB10 SH2;
PTPN11 SH2;
SH2B1 SH2
TyrKc
0.17
1IR3 44.54%
Y 1190 MTRDIYETDYYRKGGKGLLPV - 9506989
LTP
1.00
GRB10 SH2;
PTPN11 SH2;
SH2B1 SH2
TyrKc
0.17
1IR3 44.54%
Y 1190 MTRDIYETDYYRKGGKGLLPV - 18083107
HTP
1.00
GRB10 SH2;
PTPN11 SH2;
SH2B1 SH2
TyrKc
0.17
1IR3 44.54%

Substrate: RET (Probable receptor with tyrosine-protein kinase activity; important for development.)
Seq-ID: P07949 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 981 ERPDNCSEEMYRLMLQCWKQE RET 14711813
LTP
1.00
SH2B1 SH2 TyrKc
0.34
2IVS 19.65%
Y 981 ERPDNCSEEMYRLMLQCWKQE RET 14766744
LTP
1.00
SH2B1 SH2 TyrKc
0.34
2IVS 19.65%

Substrate: JAK2 (Cytoplasmic tyrosine kinase)
Seq-ID: O60674 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 813 RDLNSLFTPDYELLTENDMLP - 15767667
LTP
0.95
SH2B1 SH2 -
0.28
--


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