List of substrates found:

INF-alpha REC  STAT 2  IL-6R (gp130)  INF gamma R  c-kit  STAT 1 


Substrate: INF-alpha REC (Interferon receptor)
Seq-ID: P17181 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 466 AAKVFLRCINYVFFPSLKPSS Tyk2 8605876
LTP
1.00
STAT1 SH2;
STAT2 SH2;
STAT3 SH2;
TYK2 SH2
-
0.03
- low
Y 466 AAKVFLRCINYVFFPSLKPSS Tyk2 8700538
LTP
1.00
STAT1 SH2;
STAT2 SH2;
STAT3 SH2;
TYK2 SH2
-
0.03
- low

Substrate: STAT 2 (Transcription factor)
Seq-ID: P52630 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 690 EKVNLQERRKYLKHRLIVVSN JAK_group 7532278
LTP
1.00
STAT1 SH2;
STAT2 SH2
-
0.19
- medium

Substrate: IL-6R (gp130) (gp130 is shared by members of the IL-6 family)
Seq-ID: P40189 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 905 AATDEGMPKSYLPQTVRQGGY - 8612579
LTP
1.00
STAT1 SH2;
STAT3 SH2
-
0.70
- medium
Y 905 AATDEGMPKSYLPQTVRQGGY - 10661409
LTP
1.00
STAT1 SH2;
STAT3 SH2
-
0.70
- medium
Y 915 YLPQTVRQGGYMPQ        - 8612579
LTP
1.00
STAT1 SH2;
STAT3 SH2
-
0.64
- medium
Y 915 YLPQTVRQGGYMPQ        - 10661409
LTP
1.00
STAT1 SH2;
STAT3 SH2
-
0.64
- medium

Substrate: INF gamma R (Interferon receptor)
Seq-ID: P15260 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 457 TVIKAPTSFGYDKPHVLVDLL JAK1 8156998
LTP
1.00
STAT1 SH2 IFNGR1
0.37
- low

Substrate: c-kit (Receptor tyrosine kinase)
Seq-ID: P10721 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
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Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 823 LARDIKNDSNYVVKGNARLPV - N.N.
LTP
1.00
STAT1 SH2 TyrKc
0.18
1T46 3.93%

Substrate: STAT 1 (Transcription factor)
Seq-ID: P42224 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 701 MELDGPKGTGYIKTELISVSE - 7592750
LTP
1.00
STAT1 SH2;
STAT2 SH2
-
0.47
1BF5 139.74%
Y 701 MELDGPKGTGYIKTELISVSE - 15322115
LTP
1.00
STAT1 SH2;
STAT2 SH2
-
0.47
1BF5 139.74%
Y 701 MELDGPKGTGYIKTELISVSE JAK2 11438544
LTP
1.00
STAT1 SH2;
STAT2 SH2
-
0.47
1BF5 139.74%
Y 701 MELDGPKGTGYIKTELISVSE JAK1 11438544
LTP
1.00
STAT1 SH2;
STAT2 SH2
-
0.47
1BF5 139.74%
Y 701 MELDGPKGTGYIKTELISVSE - 10748192
LTP
1.00
STAT1 SH2;
STAT2 SH2
-
0.47
1BF5 139.74%
Y 701 MELDGPKGTGYIKTELISVSE SRC 14978237
LTP
1.00
STAT1 SH2;
STAT2 SH2
-
0.47
1BF5 139.74%
Y 701 MELDGPKGTGYIKTELISVSE JAK2 14978237
LTP
1.00
STAT1 SH2;
STAT2 SH2
-
0.47
1BF5 139.74%
Y 701 MELDGPKGTGYIKTELISVSE JAK1 14978237
LTP
1.00
STAT1 SH2;
STAT2 SH2
-
0.47
1BF5 139.74%


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