Substrate: c-kit (Receptor tyrosine kinase)
Seq-ID: P05532 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
stem cell factor receptor activity,
ATP binding,
protein binding		 external side of plasma membrane,
integral to membrane		 positive regulation of cell proliferation,
spermatid development,
cytokine-mediated signaling pathway,
germ cell programmed cell death,
regulation of developmental pigmentation,
response to radiation,
protein amino acid autophosphorylation,
chemotaxis,
myeloid progenitor cell differentiation,
negative regulation of programmed cell death,
transmembrane receptor protein tyrosine kinase signaling pathway,
peptidyl-tyrosine phosphorylation,
developmental pigmentation,
myeloid leukocyte differentiation,
glycosphingolipid metabolic process,
lymphoid progenitor cell differentiation,
positive regulation of MAP kinase activity,
cell proliferation,
intracellular protein kinase cascade,
positive regulation of gene expression
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 567 KVVEEINGNNYVYIDPTQLPY - N.N.
LTP
1.00
 - -
0.13
 - medium
Y 569 VEEINGNNYVYIDPTQLPYDH - N.N.
LTP
1.00
 - -
0.13
 - medium
Y 702 KQEEQAEAALYKNLLHSTEPS - N.N.
LTP
1.00
 - TyrKc
0.35
 - medium
Y 719 TEPSCDSSNEYMDMKPGVSYV - N.N.
LTP
1.00
 - TyrKc
0.39
 - medium
Y 719 TEPSCDSSNEYMDMKPGVSYV - 7509796
LTP
1.00
 - TyrKc
0.39
 - medium
Y 719 TEPSCDSSNEYMDMKPGVSYV - 12393643
LTP
1.00
 - TyrKc
0.39
 - medium
Y 821 LARDIRNDSNYVVKGNARLPV - N.N.
LTP
1.00
 - TyrKc
0.19
 - medium
Y 934 KQISDSTKHIYSNLANCNPNP Fyn N.N.
LTP
1.00
 - -
0.42
 - medium
Y 934 KQISDSTKHIYSNLANCNPNP Fyn 12374739
LTP
1.00
 - -
0.42
 - medium

Substrate: c-kit (Receptor tyrosine kinase)
Seq-ID: P10721 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor signaling protein tyrosine kinase activity,
ATP binding,
protein binding		 integral to membrane,
extracellular space		 male gonad development,
transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 568 KVVEEINGNNYVYIDPTQLPY Kit 9799234
LTP
1.00
 Fyn SH2;
MATK SH2;
PTPN11 SH2;
PTPN6 SH2;
SHC1 SH2		 -
0.13
 --
Y 570 VEEINGNNYVYIDPTQLPYDH Kit 9799234
LTP
1.00
 Fyn SH2;
MATK SH2;
PTPN6 SH2;
SHC1 SH2		 -
0.13
 --
Y 703 KQEDHAEAALYKNLLHSKESS Kit 10377264
LTP
1.00
 GRB2 SH2 TyrKc
0.30
 --
Y 721 ESSCSDSTNEYMDMKPGVSYV - N.N.
LTP
1.00
 MATK SH2;
PIK3R1 SH2;
PIK3R2 SH2;
SHC1 SH2		 TyrKc
0.36
 --
Y 721 ESSCSDSTNEYMDMKPGVSYV - 9038210
LTP
1.00
 MATK SH2;
PIK3R1 SH2;
PIK3R2 SH2;
SHC1 SH2		 TyrKc
0.36
 --
S 741 VVPTKADKRRSVRIGSYIERD PKC_alpha 7539802
LTP
1.00
 - TyrKc
0.30
 --
S 746 ADKRRSVRIGSYIERDVTPAI PKC_alpha 7539802
LTP
0.11
 - TyrKc
0.31
 3G0E 8.20%
S 821 FGLARDIKNDSNYVVKGNARL PKC_alpha 7539802
LTP
1.00
 - TyrKc
0.17
 1T46 90.16%
Y 823 LARDIKNDSNYVVKGNARLPV - N.N.
LTP
1.00
 STAT1 SH2 TyrKc
0.18
 1T46 3.93%
Y 900 LSPEHAPAEMYDIMKTCWDAD SRC_group 12878163
LTP
1.00
 PIK3R1 SH2 TyrKc
0.24
 1T46 16.16%
Y 900 LSPEHAPAEMYDIMKTCWDAD SRC 12878163
LTP
1.00
 PIK3R1 SH2 TyrKc
0.24
 1T46 16.16%
Y 936 KQISESTNHIYSNLANCSPNR Kit 10377264
LTP
1.00
 GRB2 SH2;
GRB7 SH2;
PLCG1 SH2		 -
0.38
 --
Y 936 KQISESTNHIYSNLANCSPNR - 18083107
HTP
1.00
 GRB2 SH2;
GRB7 SH2;
PLCG1 SH2		 -
0.38
 --
S 959 PVVDHSVRINSVGSTASSSQP PKC_alpha 7539802
LTP
0.24
 - -
0.45
 --

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