a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	SMAD1 (Transcription factor)
Seq-ID:	Q15797 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-14742   MED15_HUMAN MINT-16453   MED24_HUMAN MINT-58496   RAB3B_MOUSE MINT-58506   UBXN1_MOUSE MINT-60839   Z512B_HUMAN MINT-61985   PIAS1_HUMAN MINT-61986   XPC_HUMAN MINT-61989   NOTC2_HUMAN MINT-61990   GMEB1_HUMAN MINT-61992   ZEB2_HUMAN MINT-61993   SMAD5_HUMAN MINT-61994   TTF2_HUMAN MINT-61996   MLL2_HUMAN MINT-61997   SF3B1_HUMAN MINT-61998   RFX1_HUMAN MINT-61999   MAN1_HUMAN MINT-62001   SMAD4_HUMAN MINT-62004   SOX5_HUMAN MINT-62006   MKL2_HUMAN MINT-62007   TTF1_HUMAN MINT-62009   CASL_HUMAN MINT-62011   INP4A_HUMAN MINT-62014   PUM1_HUMAN MINT-62015   PSB4_HUMAN MINT-62016   ANR27_HUMAN MINT-62017   MGAP_HUMAN MINT-62018   I2BP1_HUMAN MINT-62019   ICK_HUMAN MINT-62024   PSMD1_HUMAN MINT-62025   ZN251_HUMAN MINT-62027   HBP1_HUMAN MINT-62028   RU17_HUMAN MINT-4298089   TBA4A_HUMAN MINT-4298190   ANDR_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process I-SMAD binding, identical protein binding, protein kinase binding, co-SMAD binding, transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity, sequence-specific DNA binding transcription factor activity nuclear inner membrane, cytosol, integral to membrane embryonic pattern specification, primary microRNA processing, transcription, BMP signaling pathway, SMAD protein complex assembly, transforming growth factor beta receptor signaling pathway
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	462	TQMGSPHNPISSVS	BMPR1B	9136927	LTP	0.94		-	-	0.47	1KHU	46.72%
S	462	TQMGSPHNPISSVS	BMPR1B	9335504	LTP	0.94		-	-	0.47	1KHU	46.72%
S	463	QMGSPHNPISSVS	BMPR1B	9136927	LTP	0.04		-	-	0.42	1KHU	104.10%
S	463	QMGSPHNPISSVS	BMPR1B	9335504	LTP	0.04		-	-	0.42	1KHU	104.10%
S	465	GSPHNPISSVS	BMPR1B	9136927	LTP	0.00		-	-	0.30	1KHU	124.59%
S	465	GSPHNPISSVS	BMPR1B	9335504	LTP	0.00		-	-	0.30	1KHU	124.59%

Substrate:	SMAD2 (Transcription regulatory protein)
Seq-ID:	Q15796 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-15900   SMAD4_HUMAN MINT-17220   MED24_HUMAN MINT-17344   MED15_HUMAN MINT-60922   KAP0_HUMAN MINT-60926   ZEB2_HUMAN MINT-60929   NAGK_HUMAN MINT-61580   RANB9_HUMAN MINT-61581   BAZ1A_HUMAN MINT-61583   AFAD_HUMAN MINT-61584   DNJC7_HUMAN MINT-61585   ROCK1_HUMAN MINT-61587   CBP_HUMAN MINT-61589   EF1A1_HUMAN MINT-61590   RXRA_HUMAN MINT-61591   NCOA6_HUMAN MINT-61593   UBR5_HUMAN MINT-61594   P66B_HUMAN MINT-61597   IMB1_HUMAN MINT-61598   F10A1_HUMAN MINT-61599   PLIN3_HUMAN MINT-61600   SNAPN_HUMAN MINT-61601   RS14_HUMAN MINT-61605   ANC2_HUMAN MINT-61606   BCD1_HUMAN MINT-61607   ZMY11_HUMAN MINT-61610   PAPOA_HUMAN MINT-61611   KHDR1_HUMAN MINT-61615   NED4L_HUMAN MINT-61618   ST5_HUMAN MINT-61620   PEX19_HUMAN MINT-61623   CUL5_HUMAN MINT-61625   RU17_HUMAN MINT-61627   TGM2_HUMAN MINT-62063   SMAD9_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process I-SMAD binding, R-SMAD binding, co-SMAD binding, ubiquitin protein ligase binding, transcription activator activity, transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity, double-stranded DNA binding, type I transforming growth factor beta receptor binding, transcription factor binding, promoter binding, sequence-specific DNA binding transcription factor activity cytosol, activin responsive factor complex intracellular signaling pathway, paraxial mesoderm morphogenesis, regulation of binding, mesoderm formation, transcription, SMAD protein complex assembly, response to cholesterol, zygotic specification of dorsal/ventral axis, cell fate commitment, positive regulation of gene-specific transcription, negative regulation of transcription, DNA-dependent, regulation of transforming growth factor beta receptor signaling pathway, anterior/posterior pattern formation, transforming growth factor beta receptor signaling pathway, palate development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of epithelial to mesenchymal transition, common-partner SMAD protein phosphorylation, primary microRNA processing
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	464	TQMGSPSVRCSSMS	BMPR1B	9136927	LTP	0.99		-	-	0.32	1KHX	38.52%
S	465	QMGSPSVRCSSMS	BMPR1B	9136927	LTP	0.11		-	-	0.28	1KHX	168.85%
S	467	GSPSVRCSSMS	BMPR1B	9136927	LTP	0.00		-	-	0.20	1KHX	163.93%