Substrate: SMAD2 (Transcription regulatory protein)
Seq-ID: Q15796 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-15900   SMAD4_HUMAN
MINT-17220   MED24_HUMAN
MINT-17344   MED15_HUMAN
MINT-60922   KAP0_HUMAN
MINT-60926   ZEB2_HUMAN
MINT-60929   NAGK_HUMAN
MINT-61580   RANB9_HUMAN
MINT-61581   BAZ1A_HUMAN
MINT-61583   AFAD_HUMAN
MINT-61584   DNJC7_HUMAN
MINT-61585   ROCK1_HUMAN
MINT-61587   CBP_HUMAN
MINT-61589   EF1A1_HUMAN
MINT-61590   RXRA_HUMAN
MINT-61591   NCOA6_HUMAN
MINT-61593   UBR5_HUMAN
MINT-61594   P66B_HUMAN
MINT-61597   IMB1_HUMAN
MINT-61598   F10A1_HUMAN
MINT-61599   PLIN3_HUMAN
MINT-61600   SNAPN_HUMAN
MINT-61601   RS14_HUMAN
MINT-61605   ANC2_HUMAN
MINT-61606   BCD1_HUMAN
MINT-61607   ZMY11_HUMAN
MINT-61610   PAPOA_HUMAN
MINT-61611   KHDR1_HUMAN
MINT-61615   NED4L_HUMAN
MINT-61618   ST5_HUMAN
MINT-61620   PEX19_HUMAN
MINT-61623   CUL5_HUMAN
MINT-61625   RU17_HUMAN
MINT-61627   TGM2_HUMAN
MINT-62063   SMAD9_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
I-SMAD binding,
R-SMAD binding,
co-SMAD binding,
ubiquitin protein ligase binding,
transcription activator activity,
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity,
double-stranded DNA binding,
type I transforming growth factor beta receptor binding,
transcription factor binding,
promoter binding,
sequence-specific DNA binding transcription factor activity		 cytosol,
activin responsive factor complex		 intracellular signaling pathway,
paraxial mesoderm morphogenesis,
regulation of binding,
mesoderm formation,
transcription,
SMAD protein complex assembly,
response to cholesterol,
zygotic specification of dorsal/ventral axis,
cell fate commitment,
positive regulation of gene-specific transcription,
negative regulation of transcription, DNA-dependent,
regulation of transforming growth factor beta receptor signaling pathway,
anterior/posterior pattern formation,
transforming growth factor beta receptor signaling pathway,
palate development,
positive regulation of transcription from RNA polymerase II promoter,
positive regulation of epithelial to mesenchymal transition,
common-partner SMAD protein phosphorylation,
primary microRNA processing
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 8    MSSILPFTPPVVKRLLGW - 11027280
LTP
1.00
 MOD_ProDKin_1
 - -
0.29
 --
T 8    MSSILPFTPPVVKRLLGW - 17081983
HTP
1.00
 MOD_ProDKin_1
 - -
0.29
 --
T 8    MSSILPFTPPVVKRLLGW MAPK3 12193595
LTP
1.00
 MOD_ProDKin_1
 - -
0.29
 --
T 220 IEPQSNYIPETPPPGYISEDG - 11027280
LTP
0.84
 MOD_ProDKin_1
 - -
0.72
 --
T 220 IEPQSNYIPETPPPGYISEDG MAPK3 12193595
LTP
0.84
 MOD_ProDKin_1
 - -
0.72
 --
S 245 QQLNQSMDTGSPAELSPTTLS - 11027280
LTP
0.88
 MOD_ProDKin_1
 - -
0.76
 --
S 245 QQLNQSMDTGSPAELSPTTLS MAPK3 12193595
LTP
0.88
 MOD_ProDKin_1
 - -
0.76
 --
S 250 SMDTGSPAELSPTTLSPVNHS - 11027280
LTP
0.66
 MOD_ProDKin_1
 - -
0.68
 --
S 250 SMDTGSPAELSPTTLSPVNHS MAPK3 12193595
LTP
0.66
 MOD_ProDKin_1
 - -
0.68
 --
S 255 SPAELSPTTLSPVNHSLDLQP - 11027280
LTP
0.85
 MOD_ProDKin_1
 - -
0.57
 --
S 255 SPAELSPTTLSPVNHSLDLQP MAPK3 12193595
LTP
0.85
 MOD_ProDKin_1
 - -
0.57
 --
S 458 WLDKVLTQMGSPSVRCSSMS  - 18669648
HTP
0.97
 - -
0.23
 1KHX 84.43%
S 464 TQMGSPSVRCSSMS        - 9892009
LTP
0.99
 - -
0.32
 1KHX 38.52%
S 464 TQMGSPSVRCSSMS        BMPR1B 9136927
LTP
0.99
 - -
0.32
 1KHX 38.52%
S 464 TQMGSPSVRCSSMS        TGFbR1 8980228
LTP
0.99
 - -
0.32
 1KHX 38.52%
S 465 QMGSPSVRCSSMS         - 9892009
LTP
0.11
 - -
0.28
 1KHX 168.85%
S 465 QMGSPSVRCSSMS         BMPR1B 9136927
LTP
0.11
 - -
0.28
 1KHX 168.85%
S 465 QMGSPSVRCSSMS         TGFbR1 15134444
LTP
0.11
 - -
0.28
 1KHX 168.85%
S 465 QMGSPSVRCSSMS         TGFbR1 8980228
LTP
0.11
 - -
0.28
 1KHX 168.85%
S 467 GSPSVRCSSMS           - 9892009
LTP
0.00
 - -
0.20
 1KHX 163.93%
S 467 GSPSVRCSSMS           BMPR1B 9136927
LTP
0.00
 - -
0.20
 1KHX 163.93%
S 467 GSPSVRCSSMS           TGFbR1 15134444
LTP
0.00
 - -
0.20
 1KHX 163.93%
S 467 GSPSVRCSSMS           TGFbR1 8980228
LTP
0.00
 - -
0.20
 1KHX 163.93%

Valid HTML 4.01 Transitional