List of substrates found:


Substrate: CAMK4 (calcium- and calmodulin-dependent protein k...)
Seq-ID: P13234 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ATP binding,
calmodulin-dependent protein kinase activity,
calmodulin binding		 cytoplasm protein amino acid phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 437 ETDDQEMKRNSEETLKSVEEE CaM-KIV 8340352
LTP
0.16
 - -
0.94
 - low

Substrate: CREB (cAMP response element binding protein (CREB).)
Seq-ID: P16220 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-16217   BRCA1_HUMAN
MINT-56642   SGK1_HUMAN
MINT-63231   RECQ5_HUMAN
MINT-63483   VIME_HUMAN
MINT-63485   CHD3_HUMAN
MINT-4979977   CBP_HUMAN
MINT-5209851   EP300_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein dimerization activity,
transcription cofactor activity		 protein amino acid phosphorylation,
signal transduction,
interspecies interaction between organisms,
response to organic substance
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 133 KRREILSRRPSYRKILNDLSS CaM-KIV 7958915
LTP
1.00
 - pKID
0.54
 - low

Substrate: CREB-binding protein (Transcription regulatory protein)
Seq-ID: P45481 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-24802   NCOA3_HUMAN
MINT-72894   LT_SV40
MINT-4979712   CREB1_MOUSE
MINT-7264037   STAT1_HUMAN
MINT-7264052   STAT2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
DNA binding,
histone acetyltransferase activity,
chromatin binding,
MyoD binding,
transcription coactivator activity,
zinc ion binding		 outer kinetochore of condensed chromosome,
transcription factor complex,
histone acetyltransferase complex		 transcription,
positive regulation of transcription factor activity,
N-terminal peptidyl-lysine acetylation,
histone acetylation,
positive regulation of transcription from RNA polymerase II promoter,
germ-line stem cell maintenance
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 301 GVNPQLASKQSMVNSLPAFPT CaM-KIV 11970865
LTP
0.16
 - -
0.58
 --

Substrate: CREB-binding protein (Transcription regulatory protein)
Seq-ID: Q92793 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19932   NCOA1_HUMAN
MINT-61587   SMAD2_HUMAN
MINT-69566   VE7_HPV16
MINT-2632018   KAT2B_HUMAN
MINT-2982685   RUNX1_HUMAN
MINT-4652920   HIF1A_HUMAN
MINT-4790784   ARM_DROME
MINT-4979977   CREB1_HUMAN
MINT-6540731   IRF3_HUMAN
MINT-6628476   LT_SV40
MINT-6665320   P53_HUMAN
MINT-6665325   TF2B_HUMAN
MINT-6665351   E1A_ADE05
MINT-6804492   LDLR_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
histone acetyltransferase activity,
p53 binding,
MyoD binding,
transcription coactivator activity,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
signal transducer activity		 nuclear body,
cytoplasm		 homeostatic process,
protein complex assembly,
transcription,
response to hypoxia,
N-terminal peptidyl-lysine acetylation,
histone acetylation,
interspecies interaction between organisms
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 302 GVNPQLASKQSMVNSLPTFPT CaM-KIV 11970865
LTP
0.16
 - -
0.62
 --

Substrate: E1A-associated protein p300 (Transcription regulatory protein)
Seq-ID: Q09472 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-13681   P73_HUMAN
MINT-17787   GATA4_MOUSE
MINT-50178   TF65_HUMAN
MINT-69559   VE7_HPV16
MINT-2584615   TF2B_HUMAN
MINT-2831131   ABL1_HUMAN
MINT-2982535   HIPK2_HUMAN
MINT-2982660   RUNX1_HUMAN
MINT-2983397   CDK2_HUMAN
MINT-4790867   ITF2_HUMAN
MINT-4791678   HIF1A_HUMAN
MINT-4979756   CREB1_MOUSE
MINT-5209851   CREB1_HUMAN
MINT-6628502   LT_SV40
MINT-6665134   E1A_ADE05
MINT-6743403   STRAP_HUMAN
MINT-7263630   P53_HUMAN
MINT-7943702   SENP3_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
histone acetyltransferase activity,
beta-catenin binding,
transcription coactivator activity,
zinc ion binding		 cytoplasm transcription,
response to hypoxia,
histone H4 acetylation,
apoptosis,
positive regulation of transcription factor activity,
cell cycle,
N-terminal peptidyl-lysine acetylation,
interspecies interaction between organisms,
positive regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 24 KRPKLSSPALSASASDGTDFG CaM-KIV 12590608
LTP
1.00
 - -
0.66
 - medium

Substrate: HDAC5 (histone deacetylase activity, specific transcriptional repressor activity)
Seq-ID: Q9UQL6 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-65796   EF1G_HUMAN
MINT-3318337   1433Z_HUMAN
MINT-6802102   HIF1A_HUMAN
MINT-7299978   BUB1B_HUMAN
MINT-7710106   PKN2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase C binding,
transcription repressor binding,
specific transcriptional repressor activity,
histone deacetylase activity,
transcription factor binding		 histone deacetylase complex,
cytoplasm		 B cell differentiation,
negative regulation of gene-specific transcription from RNA polymerase II promoter,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
negative regulation of myotube differentiation,
transcription,
histone deacetylation,
positive regulation of transcription factor activity,
chromatin silencing,
inflammatory response,
negative regulation of cell migration involved in sprouting angiogenesis,
chromatin remodeling,
cellular response to insulin stimulus,
regulation of protein binding
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 259 RDDFPLRKTASEPNLKVRSRL CaM-KIV 11081517
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.69
 - medium
S 498 PRHRPLSRTQSSPLPQSPQAL CaM-KIV 11081517
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.88
 - medium

Substrate: Histone deacetylase 4 (Enzyme: Deacetylase)
Seq-ID: P56524 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-49703   MEF2A_HUMAN
MINT-49706   MEF2C_HUMAN
MINT-3296491   1433Z_HUMAN
MINT-3975818   1433S_HUMAN
MINT-6802058   HIF1A_HUMAN
MINT-7144512   ZN148_HUMAN
MINT-7299965   BUB1B_HUMAN
MINT-7555703   ATF2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
potassium ion binding,
transcription repressor binding,
specific transcriptional repressor activity,
transcription activator binding,
transcription activator activity,
histone deacetylase activity,
histone deacetylase binding,
zinc ion binding		 histone deacetylase complex,
transcriptional repressor complex		 B cell differentiation,
negative regulation of gene-specific transcription from RNA polymerase II promoter,
nervous system development,
positive regulation of cell proliferation,
negative regulation of transcription factor activity,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
negative regulation of myotube differentiation,
transcription,
histone H4 deacetylation,
positive regulation of transcription factor activity,
response to denervation involved in regulation of muscle adaptation,
inflammatory response,
histone H3 deacetylation,
response to interleukin-1,
chromatin remodeling,
cardiac muscle hypertrophy in response to stress,
negative regulation of glycolysis,
positive regulation of protein sumoylation,
peptidyl-lysine deacetylation,
regulation of protein binding
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 467 RQHRPLGRTQSAPLPQNAQAL CaM-KIV 11470791
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.84
 - low
S 632 GGHRPLSRAQSSPASATFPVS CaM-KIV 11470791
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.67
 - low

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