List of substrates found:


Substrate: Alpha-synuclein (Chaperone)
Seq-ID: P37840 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-2515544   VIME_HUMAN
MINT-3387974   TPPP_HUMAN
MINT-7555062   HSP71_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
histone binding,
ferrous iron binding,
phospholipase binding,
caspase inhibitor activity,
dynein binding,
alpha-tubulin binding,
zinc ion binding,
Hsp70 protein binding,
kinesin binding,
magnesium ion binding,
calcium ion binding,
tau protein binding		 plasma membrane,
cytosol,
nucleus,
axon,
actin cytoskeleton,
cell cortex,
growth cone,
fibril		 response to magnesium ion,
positive regulation of release of sequestered calcium ion into cytosol,
response to interferon-gamma,
regulation of phospholipase activity,
negative regulation of platelet-derived growth factor receptor signaling pathway,
positive regulation of inositol phosphate biosynthetic process,
response to interleukin-1,
response to iron(II) ion,
synaptic vesicle endocytosis,
negative regulation of monooxygenase activity,
positive regulation of receptor recycling,
response to lipopolysaccharide,
negative regulation of norepinephrine uptake,
negative regulation of exocytosis,
negative regulation of histone acetylation,
negative regulation of serotonin uptake,
receptor internalization,
cell death,
negative regulation of dopamine uptake,
negative regulation of transporter activity,
negative regulation of thrombin receptor signaling pathway,
positive regulation of endocytosis,
anti-apoptosis,
negative regulation of caspase activity
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 87 VAQKTVEGAGSIAAATGFVKK DYRK1A 16959772
LTP
0.10
 - Synuclein
0.39
 --

Substrate: Amphiphysin (Amphiphysin)
Seq-ID: P49418 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-16056   SYNJ1_HUMAN
MINT-50453   AP2A2_MOUSE
MINT-65945   DYN1_HUMAN
MINT-2516534   DYN2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cell junction,
synaptic vesicle membrane,
actin cytoskeleton		 synaptic transmission
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 293 PASPAPARPRSPSQTRKGPPV DYRK1A 16733250
LTP
1.00
 - -
0.93
 - medium

Substrate: Dynamin 1 (Dynamin-1)
Seq-ID: Q05193 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-65945   AMPH_HUMAN
MINT-65948   ITSN1_HUMAN
MINT-65949   SH3G2_HUMAN
MINT-65952   GRB2_HUMAN
MINT-65953   SRC_HUMAN
MINT-7102122   MYO1E_HUMAN
MINT-7244638   ABL1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
GTPase activity,
GTP binding,
motor activity,
protein binding		 microtubule receptor-mediated endocytosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 857 SGQASPSRPESPRPPFDL    DYRK1A 15287745
LTP
0.22
 - -
0.97
 - medium

Substrate: Forkhead box protein O1A (Forkhead box protein O1A)
Seq-ID: Q12778 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
transcription activator activity,
protein binding		 cytosol,
nucleoplasm		 transcription,
anti-apoptosis,
negative regulation of stress-activated MAPK cascade,
positive regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 329 SNASTISGRLSPIMTEQDDLG DYRK1A 11311120
LTP
1.00
 - -
0.75
 - medium

Substrate: Spry-2 (Adaptor molecule)
Seq-ID: O43597 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-6169734   GRB2_HUMAN
MINT-6170603   SH3K1_HUMAN
MINT-6539601   CBL_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
plasma membrane,
cytosol,
microtubule		 signal transduction,
cell-cell signaling
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 75 PGLKPAPRPSTQHKHERLHGL DYRK1A 18678649
LTP
0.36
 - -
0.95
 - medium

Valid HTML 4.01 Transitional