a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	cdc25A (Dual specificity phosphatase)
Seq-ID:	P30304 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-15591   CHK2_HUMAN MINT-3294407   1433Z_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein tyrosine phosphatase activity, protein binding nucleoplasm regulation of cyclin-dependent protein kinase activity, cell division, protein amino acid dephosphorylation, mitosis, DNA replication, cell proliferation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	116	HSLPQKLLGCSPALKRSHSDS	PIM-1	12411508	LTP	1.00		-	M-inducer_phosp	0.51	-	high

Substrate:	p21 (Cyclin-dependent kinase inhibitor 1 (p21))
Seq-ID:	P38936 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-50392   CC45L_HUMAN MINT-50407   CDC6_HUMAN MINT-50418   CDK4_HUMAN MINT-50421   CDK6_HUMAN MINT-50432   CCNB2_HUMAN MINT-50437   CCND1_HUMAN MINT-50441   CCND3_HUMAN MINT-50445   GEMI_HUMAN MINT-50660   CCNB1_HUMAN MINT-73322   VE7_HPV16 MINT-73323   CDK2_HUMAN MINT-1774121   SKP2_HUMAN MINT-1780042   MCM7_HUMAN MINT-1891378   P53_HUMAN MINT-2635177   CCNE1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process cyclin-dependent protein kinase inhibitor activity, metal ion binding cytosol, cyclin-dependent protein kinase holoenzyme complex, nucleoplasm, PCNA-p21 complex cellular response to extracellular stimulus, positive regulation of fibroblast proliferation, senescence, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, negative regulation of cell proliferation, negative regulation of cell growth, cell cycle arrest, G1/S transition of mitotic cell cycle, induction of apoptosis by intracellular signals, Ras protein signal transduction, G2/M transition of mitotic cell cycle
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	145	GDSQGRKRRQTSMTDFYHSKR	PIM-1	17855660	LTP	0.19	MOD_PKB_1	-	-	0.69	-	medium
S	146	DSQGRKRRQTSMTDFYHSKRR	PIM-1	17855660	LTP	0.03	MOD_PKB_1	-	-	0.65	-	medium