Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

ci
ftz
Lamin Dm0
Lsd-1
ple
REL
slo

ci (Protein cubitus interruptus)

Seq-ID:

P19538 [Drosophila melanogaster]

Download:

Interaction Network(s):

STRING

External Source(s):

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, transcription activator activity, zinc ion binding, sequence-specific DNA binding transcription factor activity, protein binding	cytoplasm, nucleus, membrane, Hedgehog signaling complex	epidermis development, wing disc anterior/posterior pattern formation, genital disc anterior/posterior pattern formation, heart formation, segment polarity determination, spiracle morphogenesis, open tracheal system, eye morphogenesis, ovarian follicle cell development, smoothened signaling pathway, cuticle pattern formation, positive regulation of epithelial cell differentiation, positive regulation of S phase of mitotic cell cycle, labial disc development, positive regulation of transcription from RNA polymerase II promoter, dendrite morphogenesis, negative regulation of transcription from RNA polymerase II promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	856	YYGSMQSRRSSQSSQVSSIPT	PKA_group_drome	10557210	LTP	1.00	MOD_PKA_1	-	-	0.69	-	medium
S	856	YYGSMQSRRSSQSSQVSSIPT	PKA_group_drome	10477300	LTP	1.00	MOD_PKA_1	-	-	0.69	-	medium
S	856	YYGSMQSRRSSQSSQVSSIPT	PKA_group_drome	9461217	LTP	1.00	MOD_PKA_1	-	-	0.69	-	medium
S	856	YYGSMQSRRSSQSSQVSSIPT	PKA_group_drome	16326393	LTP	1.00	MOD_PKA_1	-	-	0.69	-	medium
S	892	PISPGCSRRSSQMSNGANCNS	PKA_group_drome	10557210	LTP	0.87	MOD_PKA_1	-	-	0.56	-	medium
S	892	PISPGCSRRSSQMSNGANCNS	PKA_group_drome	10477300	LTP	0.87	MOD_PKA_1	-	-	0.56	-	medium
S	892	PISPGCSRRSSQMSNGANCNS	PKA_group_drome	9461217	LTP	0.87	MOD_PKA_1	-	-	0.56	-	medium
S	892	PISPGCSRRSSQMSNGANCNS	PKA_group_drome	16326393	LTP	0.87	MOD_PKA_1	-	-	0.56	-	medium

ftz (Segmentation protein fushi tarazu)

Seq-ID:

P02835 [Drosophila melanogaster]

Download:

Interaction Network(s):

STRING

External Source(s):

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, protein binding	nucleus	central nervous system development, transcription, regulation of transcription from RNA polymerase II promoter, periodic partitioning by pair rule gene, germ cell migration, negative regulation of transcription, DNA-dependent, gonadal mesoderm development, trunk segmentation, cell fate specification, posterior head segmentation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	262	KDSKRTRQTYTRYQTLELEKE	PKA_group_drome	9545243	LTP	1.00	MOD_PKA_2	-	HOX	0.54	-	-
T	262	KDSKRTRQTYTRYQTLELEKE	PKA_group_drome	10370126	LTP	1.00	MOD_PKA_2	-	HOX	0.54	-	-

Lamin Dm0 (lamin Dm0 (from PhosphoBase))

Seq-ID:

P08928 [Drosophila melanogaster]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

MINT Interaction(s):

[show]

MINT-42096 IMA_DROME
MINT-42822 OTE_DROME

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural molecule activity, receptor binding	lipid particle, microtubule associated complex, lamin filament, nuclear envelope	gonad morphogenesis, terminal branching, open tracheal system, central nervous system development, compound eye morphogenesis, nuclear migration, chromatin silencing, chitin-based cuticle development, mitotic nuclear envelope reassembly, digestive tract morphogenesis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	50	ASSPLSPTRHSRVAEKVELQN	PKA_group_drome	9013881	LTP	1.00	MOD_PKA_2	-	-	0.80	-	medium

Lsd-1 (Lipid storage droplets surface-binding protein 1)

Seq-ID:

Q9VCI3 [Drosophila melanogaster]

Download:

Interaction Network(s):

STRING

External Source(s):

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	lipid particle	lipid storage, lipid transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	20	LHLEAIDRIGSIPLVESSVKR	PKA_group_drome	18342616	LTP	1.00		-	Perilipin	0.17	-	medium

ple (Tyrosine 3-monooxygenase)

Seq-ID:

P18459 [Drosophila melanogaster]

Download:

Interaction Network(s):

STRING

External Source(s):

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
iron ion binding, tyrosine 3-monooxygenase activity, protein binding		dopamine biosynthetic process, neurotransmitter biosynthetic process, oxidation reduction, male courtship behavior, adult locomotory behavior, aromatic amino acid family metabolic process, developmental pigmentation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	32	IENGYPSRRRSLVDDARFETL	PKA_group_drome	10358021	LTP	1.00	MOD_PKA_1	-	-	0.49	-	medium

REL (c-Rel proto-oncogene protein (p68) (from PhosphoBase))

Seq-ID:

Q94527 [Drosophila melanogaster]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, transcription activator activity, sequence-specific DNA binding transcription factor activity, protein binding	cytoplasm, nucleus	cellular response to amino acid starvation, Toll signaling pathway, positive regulation of antifungal peptide biosynthetic process, positive regulation of gene-specific transcription from RNA polymerase II promoter, transcription, positive regulation of nitric oxide biosynthetic process, defense response to virus, signal transduction, innate immune response, peripheral nervous system neuron development, defense response to Gram-negative bacterium, positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, antimicrobial humoral response, positive regulation of innate immune response

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	431	VNVYIELIRPSDDERSFPALP	PKA_group_drome	19135474	LTP	0.98	MOD_PKA_2	-	IPT	0.32	-	low

slo (Calcium-activated potassium channel slowpoke)

Seq-ID:

Q03720 [Drosophila melanogaster]

Download:

Interaction Network(s):

External Source(s):

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
catalytic activity, calcium-activated potassium channel activity, voltage-gated potassium channel activity, protein binding	neuronal cell body, neuron projection, voltage-gated potassium channel complex	male courtship behavior, veined wing generated song production, circadian behavior, response to drug

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	978	GSPIVLQRRGSVYGANVPMIT	PKA_group_drome	12019304	LTP	0.22	MOD_PKA_1	-	-	0.23	-	medium
S	978	GSPIVLQRRGSVYGANVPMIT	PKA_group_drome	10234050	LTP	0.22	MOD_PKA_1	-	-	0.23	-	medium