List of substrates found:


Substrate: BAD (Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl- XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein))
Seq-ID: Q92934 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14699   B2CL1_HUMAN
MINT-66103   1433S_HUMAN
MINT-7034091   B2L11_HUMAN
MINT-7717137   NAF1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase binding cytosol,
mitochondrial outer membrane		 induction of apoptosis by extracellular signals,
activation of pro-apoptotic gene products
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 75 GAVEIRSRHSSYPAGTEDDEG RSK-1 10837486
LTP
0.32
 MOD_PKA_2
 - Bcl-2_BAD
0.83
 - medium
S 118 QRYGRELRRMSDEFVDSFKKG RSK-1 10837486
LTP
0.77
 - Bcl-2_BAD
0.56
 - medium

Substrate: C/EBP beta (Transcription factor)
Seq-ID: P17676 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-14023   SMAD3_HUMAN
MINT-14687   SMAD4_HUMAN
MINT-49733   HMGA1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
RNA polymerase II transcription factor activity, enhancer binding transcription from RNA polymerase II promoter,
immune response,
acute-phase response
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 266 PSQVKSKAKKTVDKHSDEYKI RSK-1 10635333
LTP
0.10
 - -
0.71
 --

Substrate: ER81 (Ets translocation variant 1)
Seq-ID: P50549 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
sequence-specific DNA binding transcription factor activity		 nucleus transcription from RNA polymerase II promoter,
regulation of transcription, DNA-dependent
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 191 PMDHRFRRQLSEPCNSFPPLP RSK-1 12213813
LTP
1.00
 - ETS_PEA3_N
0.57
 - low
S 216 EGRPMYQRQMSEPNIPFPPQG RSK-1 12213813
LTP
1.00
 - ETS_PEA3_N
0.79
 - low
S 334 REGPTYQRRGSLQLWQFLVAL RSK-1 12213813
LTP
0.97
 - ETS
0.15
 - low

Substrate: Estrogen receptor beta (Estrogen receptor beta)
Seq-ID: Q92731 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor antagonist activity,
steroid binding,
transcription coactivator activity,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
estrogen receptor activity		 mitochondrion,
nucleus		 transcription,
negative regulation of cell growth,
cell-cell signaling
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 165 YASGYHYGVWSCEGCKAFFKR RSK-1 9528769
LTP
1.00
 - ZnF_C4
0.04
 - medium

Substrate: Insulin receptor substrate 1 (After phosphorylation by insulin receptor binds to various cellular proteins containing SH2 domains.)
Seq-ID: P35568 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19010   INSR_HUMAN
MINT-68735   P85A_HUMAN
MINT-74551   EGFR_HUMAN
MINT-74553   ERBB2_HUMAN
MINT-3975430   1433S_HUMAN
MINT-6628637   LT_SV40
MINT-6793745   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
phosphoinositide 3-kinase binding,
protein kinase C binding,
insulin-like growth factor receptor binding,
insulin receptor binding,
transmembrane receptor protein tyrosine kinase docking protein activity,
SH2 domain binding		 microsome,
caveola,
cytosol,
insulin receptor complex,
nucleus		 negative regulation of insulin receptor signaling pathway,
glucose homeostasis,
positive regulation of insulin receptor signaling pathway,
positive regulation of fatty acid beta-oxidation,
phosphoinositide 3-kinase cascade,
negative regulation of insulin secretion,
positive regulation of glycogen biosynthetic process,
insulin receptor signaling pathway,
positive regulation of glucose import,
positive regulation of phosphoinositide 3-kinase activity
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 1101 DPQGCRRRHSSETFSSTPSAT RSK-1 17709744
LTP
1.00
 - -
0.78
 --

Substrate: NFKBIB (protein binding, signal transducer activity)
Seq-ID: Q15653 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-47839   IKBA_HUMAN
MINT-47849   RPA34_HUMAN
MINT-47851   REL_HUMAN
MINT-47853   IKKA_HUMAN
MINT-47854   IKKB_HUMAN
MINT-47855   NEMO_HUMAN
MINT-47857   IMA2_HUMAN
MINT-47861   NFKB1_HUMAN
MINT-47864   RPA49_HUMAN
MINT-47872   RPAC1_HUMAN
MINT-48722   NFKB2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription coactivator activity,
signal transducer activity		 nucleus transcription
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 19 KAADADEWCDSGLGSLGPDAA RSK-1 16822942
LTP
1.00
 BTRC WD40 -
0.37
 - low
S 23 ADEWCDSGLGSLGPDAAAPGG RSK-1 16822942
LTP
1.00
 BTRC WD40 -
0.43
 - low

Substrate: Protein phosphatase 1, regulatory subunit 3A (Serine/threonine phosphatase)
Seq-ID: Q16821 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
integral to membrane glycogen metabolic process
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 48 SPQPSRRGSDSSEDIYLDTPS RSK-1 2152882
LTP
1.00
 MOD_PKA_1
 - -
0.68
 - medium

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