Substrate: BAD (Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl- XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein))
Seq-ID: O35147 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase B binding,
protein phosphatase 2B binding		 cytosol,
mitochondrial outer membrane		 response to amino acid stimulus,
response to hypoxia,
response to hydrogen peroxide,
response to organic cyclic substance,
apoptosis,
response to drug,
response to oleic acid,
response to progesterone stimulus,
response to estradiol stimulus,
response to glucose stimulus,
response to calcium ion,
response to testosterone stimulus,
induction of apoptosis,
response to glucocorticoid stimulus,
response to ethanol
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 129 EEDEGMEEELSPFRGRSRSAP CDK1 12049737
LTP
0.47
 MOD_CDK_SPxK_1
 - Bcl-2_BAD
0.86
 - medium

Substrate: BAD (Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl- XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein))
Seq-ID: Q61337 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cytosol,
mitochondrial outer membrane		 induction of apoptosis by extracellular signals,
glucose homeostasis,
cytokine-mediated signaling pathway,
apoptosis,
positive regulation of B cell differentiation,
positive regulation of T cell differentiation,
glucose catabolic process,
cell proliferation,
regulation of caspase activity
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 112 GAMETRSRHSSYPAGTEEDEG PKB_group 9381178
LTP
1.00
 MOD_PKB_1
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.88
 - medium
S 112 GAMETRSRHSSYPAGTEEDEG PKB_group 10949026
LTP
1.00
 MOD_PKB_1
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.88
 - medium
S 112 GAMETRSRHSSYPAGTEEDEG - 15849194
LTP
1.00
 MOD_PKB_1
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.88
 - medium
S 112 GAMETRSRHSSYPAGTEEDEG RSK_group 10880354
LTP
1.00
 MOD_PKB_1
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.88
 - medium
S 112 GAMETRSRHSSYPAGTEEDEG - 17242355
HTP
1.00
 MOD_PKB_1
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.88
 - medium
S 112 GAMETRSRHSSYPAGTEEDEG RSK_group 16103085
LTP
1.00
 MOD_PKB_1
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.88
 - medium
S 112 GAMETRSRHSSYPAGTEEDEG PKB_group 11983683
LTP
1.00
 MOD_PKB_1
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.88
 - medium
T 117 RSRHSSYPAGTEEDEGMEEEL CK2_alpha 15234118
LTP
0.93
 - Bcl-2_BAD
0.87
 - medium
S 128 EEDEGMEEELSPFRGRSRSAP MAPK8 12189144
LTP
0.92
 MOD_ProDKin_1
 - Bcl-2_BAD
0.86
 - medium
S 136 ELSPFRGRSRSAPPNLWAAQR PKB_group 9381178
LTP
1.00
 MOD_PKB_1
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.66
 - medium
S 136 ELSPFRGRSRSAPPNLWAAQR PKB_group 10949026
LTP
1.00
 MOD_PKB_1
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.66
 - medium
S 155 QRYGRELRRMSDEFEGSFKGL RSK_group 10837486
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.60
 - medium
S 155 QRYGRELRRMSDEFEGSFKGL - 10837473
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.60
 - medium
S 155 QRYGRELRRMSDEFEGSFKGL - 15123689
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.60
 - medium
S 155 QRYGRELRRMSDEFEGSFKGL RSK_group 10880354
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 Bcl-2_BAD
0.60
 - medium
S 170 GSFKGLPRPKSAGTATQMRQS - 11717309
LTP
1.00
 - Bcl-2_BAD
0.79
 - medium
T 201 WDRNLGKGGSTPSQ        MAPK8 14967141
LTP
0.59
 MOD_ProDKin_1
 - Bcl-2_BAD
0.78
 - medium

Substrate: BAD (Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl- XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein))
Seq-ID: Q92934 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14699   B2CL1_HUMAN
MINT-66103   1433S_HUMAN
MINT-7034091   B2L11_HUMAN
MINT-7717137   NAF1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase binding cytosol,
mitochondrial outer membrane		 induction of apoptosis by extracellular signals,
activation of pro-apoptotic gene products
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 75 GAVEIRSRHSSYPAGTEDDEG RSK-1 10837486
LTP
0.32
 MOD_PKA_2
 - Bcl-2_BAD
0.83
 - medium
S 75 GAVEIRSRHSSYPAGTEDDEG - 15037618
LTP
0.32
 MOD_PKA_2
 - Bcl-2_BAD
0.83
 - medium
S 75 GAVEIRSRHSSYPAGTEDDEG - 15972258
LTP
0.32
 MOD_PKA_2
 - Bcl-2_BAD
0.83
 - medium
S 75 GAVEIRSRHSSYPAGTEDDEG PKA_group 15226424
LTP
0.32
 MOD_PKA_2
 - Bcl-2_BAD
0.83
 - medium
S 75 GAVEIRSRHSSYPAGTEDDEG RSK_group 14678993
LTP
0.32
 MOD_PKA_2
 - Bcl-2_BAD
0.83
 - medium
S 75 GAVEIRSRHSSYPAGTEDDEG RSK-2 10558990
LTP
0.32
 MOD_PKA_2
 - Bcl-2_BAD
0.83
 - medium
Y 76 AVEIRSRHSSYPAGTEDDEGM - 18669648
HTP
0.26
 - Bcl-2_BAD
0.84
 - medium
S 99 EPSPFRGRSRSAPPNLWAAQR PKB_group 11020382
LTP
1.00
 MOD_PKB_1
 - Bcl-2_BAD
0.76
 - medium
S 99 EPSPFRGRSRSAPPNLWAAQR - 11577096
LTP
1.00
 MOD_PKB_1
 - Bcl-2_BAD
0.76
 - medium
S 99 EPSPFRGRSRSAPPNLWAAQR - 15037618
LTP
1.00
 MOD_PKB_1
 - Bcl-2_BAD
0.76
 - medium
S 99 EPSPFRGRSRSAPPNLWAAQR - 16044149
LTP
1.00
 MOD_PKB_1
 - Bcl-2_BAD
0.76
 - medium
S 99 EPSPFRGRSRSAPPNLWAAQR PAK1 10611223
LTP
1.00
 MOD_PKB_1
 - Bcl-2_BAD
0.76
 - medium
S 99 EPSPFRGRSRSAPPNLWAAQR RSK_group 10558990
LTP
1.00
 MOD_PKB_1
 - Bcl-2_BAD
0.76
 - medium
S 99 EPSPFRGRSRSAPPNLWAAQR - 18220336
HTP
1.00
 MOD_PKB_1
 - Bcl-2_BAD
0.76
 - medium
S 99 EPSPFRGRSRSAPPNLWAAQR - 18669648
HTP
1.00
 MOD_PKB_1
 - Bcl-2_BAD
0.76
 - medium
S 118 QRYGRELRRMSDEFVDSFKKG RSK-1 10837486
LTP
0.77
 - Bcl-2_BAD
0.56
 - medium
S 118 QRYGRELRRMSDEFVDSFKKG - 18669648
HTP
0.77
 - Bcl-2_BAD
0.56
 - medium

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