List of substrates found:


Substrate: Dual specificity phosphatase 3 (Dual specificity phosphatase)
Seq-ID: P51452 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 138 YSRSPTLVIAYLMMRQKMDVK ZAP70 12447358
LTP
1.00
- DSPc
0.17
1VHR 3.93%

Substrate: Gab2 (Adaptor molecule)
Seq-ID: Q9UQC2 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 614 APKKSTGSVDYLALDFQPSSP ZAP70 11572860
LTP
0.96
PTPN11 SH2;
SHC1 SH2
-
0.69
- low

Substrate: HIP55 (Adapter molecule)
Seq-ID: Q9UJU6 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
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Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 334 CLVQAEEEAVYEEPPEQETFY ZAP70 14557276
LTP
0.14
- -
0.71
- medium
Y 344 YEEPPEQETFYEQPPLVQQQG ZAP70 14557276
LTP
1.00
- -
0.79
- medium

Substrate: LAT (Adaptor molecule involved in the TCR signal pathway)
Seq-ID: O54957 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 136 DEDEDDYPNGYLVVLPDSSPA ZAP70 11368773
LTP
0.00
PLCG_group SH2 -
0.77
- low
Y 136 DEDEDDYPNGYLVVLPDSSPA ZAP70 11457888
LTP
0.00
PLCG_group SH2 -
0.77
- low
Y 175 SAFSVESCEDYVNVPESEESA ZAP70 11368773
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
VAV_group SH2
-
0.71
- low
Y 195 AEASLDGSREYVNVSPEQQPV ZAP70 11368773
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
VAV_group SH2
-
0.83
- low
Y 235 EGVDGEEAPDYENLQELN    ZAP70 11368773
LTP
1.00
GRB2 SH2;
VAV_group SH2
-
0.90
- low

Substrate: LNK (Adapter molecule)
Seq-ID: Q9UQQ2 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
Molecular FunctionCellular ComponentBiological Process
signal transducer activity
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 273 CTRLEMPDNLYTFVLKVKDRT ZAP70 9169414
LTP
0.03
- PH
0.22
- medium

Substrate: Mitogen-activated protein kinase 14 (Mitogen-activated protein kinase 14)
Seq-ID: Q16539 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
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Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 323 DPDDEPVADPYDQSFESRDLL ZAP70 15735648
LTP
0.84
- -
0.52
2FST 9.17%

Substrate: Shc ( Adaptor molecule)
Seq-ID: P29353 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 349 EEEEEPPDHQYYNDFPGKEPP ZAP70 9710204
LTP
1.00
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.86
--
Y 350 EEEEPPDHQYYNDFPGKEPPL ZAP70 9710204
LTP
1.00
GRB2 SH2;
INPP5D SH2
-
0.85
--
Y 427 PGRELFDDPSYVNVQNLDKAR ZAP70 9710204
LTP
0.99
GRAP2 SH2;
GRB2 SH2;
INPP5D SH2
-
0.62
--

Substrate: SLP-76 (Adaptor molecule; involved in T cell AG receptor mediate signaling)
Seq-ID: Q13094 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 113 GGWSSFEEDDYESPNDDQDGE ZAP70 9047237
LTP
0.99
ITK SH2;
NCK SH2;
PIK3R1 SH2;
PTPN6 SH2;
VAV1 SH2;
VAV_group SH2
-
0.92
- medium
Y 113 GGWSSFEEDDYESPNDDQDGE ZAP70 12817019
LTP
0.99
ITK SH2;
NCK SH2;
PIK3R1 SH2;
PTPN6 SH2;
VAV1 SH2;
VAV_group SH2
-
0.92
- medium
Y 113 GGWSSFEEDDYESPNDDQDGE ZAP70 8702662
LTP
0.99
ITK SH2;
NCK SH2;
PIK3R1 SH2;
PTPN6 SH2;
VAV1 SH2;
VAV_group SH2
-
0.92
- medium
Y 128 DDQDGEDDGDYESPNEEEEAP ZAP70 9047237
LTP
0.30
ITK SH2;
NCK SH2;
PIK3R1 SH2;
PTPN6 SH2;
VAV1 SH2;
VAV_group SH2
-
0.98
- medium
Y 128 DDQDGEDDGDYESPNEEEEAP ZAP70 12817019
LTP
0.30
ITK SH2;
NCK SH2;
PIK3R1 SH2;
PTPN6 SH2;
VAV1 SH2;
VAV_group SH2
-
0.98
- medium
Y 128 DDQDGEDDGDYESPNEEEEAP ZAP70 8702662
LTP
0.30
ITK SH2;
NCK SH2;
PIK3R1 SH2;
PTPN6 SH2;
VAV1 SH2;
VAV_group SH2
-
0.98
- medium
Y 145 EEAPVEDDADYEPPPSNDEEA ZAP70 8892604
LTP
1.00
ITK SH2;
NCK SH2;
PTPN6 SH2;
VAV1 SH2
-
0.97
- medium

Substrate: ZAP70 (Cytoplasmic tyrosine kinase)
Seq-ID: P43403 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 126 DCLRDAMVRDYVRQTWKLEGE ZAP70 7961936
LTP
0.96
- -
0.16
2OQ1 39.30%
Y 292 RRIDTLNSDGYTPEPARITSP ZAP70 8756661
LTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 292 RRIDTLNSDGYTPEPARITSP ZAP70 7961936
LTP
1.00
CBL PTB;
CBL SH2;
CRKL SH2
-
0.65
--
Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 11828374
LTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 7798261
LTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 315 PRPMPMDTSVYESPYSDPEEL ZAP70 10037717
LTP
1.00
CRKL SH2;
CRK SH2;
PLCG1 SH2;
PLCG_group SH2;
VAV1 SH2;
VAV_group SH2
-
0.69
2OZO 6.42%
Y 492 LSKALGADDSYYTARSAGKWP ZAP70 8756661
LTP
1.00
Fyn SH2 TyrKc
0.14
1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP ZAP70 7961936
LTP
1.00
Fyn SH2 TyrKc
0.14
1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP ZAP70 7642520
LTP
1.00
Fyn SH2 TyrKc
0.14
1U59 13.10%
Y 492 LSKALGADDSYYTARSAGKWP ZAP70 11270871
LTP
1.00
Fyn SH2 TyrKc
0.14
1U59 13.10%
Y 493 SKALGADDSYYTARSAGKWPL ZAP70 8756661
LTP
1.00
Fyn SH2 TyrKc
0.13
1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL ZAP70 7961936
LTP
1.00
Fyn SH2 TyrKc
0.13
1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL ZAP70 7642520
LTP
1.00
Fyn SH2 TyrKc
0.13
1U59 68.12%
Y 493 SKALGADDSYYTARSAGKWPL ZAP70 11270871
LTP
1.00
Fyn SH2 TyrKc
0.13
1U59 68.12%

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