Substrate: AOF2 (demethylase)
Seq-ID: O60341 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-63172   SETB1_HUMAN
MINT-63174   CC90B_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription repressor activity,
histone demethylase activity (H3-K9 specific),
ligand-dependent nuclear receptor transcription coactivator activity,
androgen receptor binding,
chromatin binding,
oxidoreductase activity,
histone demethylase activity (H3-dimethyl-K4 specific),
FAD binding,
promoter binding		 nucleus negative regulation of gene-specific transcription from RNA polymerase II promoter,
negative regulation of transcription factor activity,
transcription,
oxidation reduction,
regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor,
multicellular organismal development
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 59 EVGPGAVGERTPRKKEPPRAS - 18669648
HTP
 - - -
0.96
 --
S 80 PPGGLAEPPGSAGPQAGPTVV - 18669648
HTP
0.59
 - -
0.96
 --
T 104 ATPMETGIAETPEGRRTSRRK - 18669648
HTP
0.48
 - -
0.93
 --
S 126 AKVEYREMDESLANLSEDEYY - 17081983
HTP
0.08
 - -
0.69
 --
S 126 AKVEYREMDESLANLSEDEYY - 18669648
HTP
0.08
 - -
0.69
 --
S 131 REMDESLANLSEDEYYSEEER - 15302935
HTP
0.21
 - -
0.77
 --
S 131 REMDESLANLSEDEYYSEEER - 17081983
HTP
0.21
 - -
0.77
 --
S 131 REMDESLANLSEDEYYSEEER - 18669648
HTP
0.21
 - -
0.77
 --
Y 135 ESLANLSEDEYYSEEERNAKA - 18669648
HTP
0.04
 - -
0.78
 --
Y 136 SLANLSEDEYYSEEERNAKAE - 18669648
HTP
0.04
 - -
0.77
 --
S 137 LANLSEDEYYSEEERNAKAEK - 15302935
HTP
0.13
 - -
0.77
 --
S 137 LANLSEDEYYSEEERNAKAEK - 17081983
HTP
0.13
 - -
0.77
 --
S 137 LANLSEDEYYSEEERNAKAEK - 18669648
HTP
0.13
 - -
0.77
 --
S 166 PQAPPEEENESEPEEPSGVEG - 15302935
HTP
1.00
 - -
0.97
 --
S 166 PQAPPEEENESEPEEPSGVEG - 17081983
HTP
1.00
 - -
0.97
 --
S 166 PQAPPEEENESEPEEPSGVEG - 18220336
HTP
1.00
 - -
0.97
 --
S 166 PQAPPEEENESEPEEPSGVEG - 18669648
HTP
1.00
 - -
0.97
 --
S 849 QATPGVPAQQSPSM        - 18669648
HTP
0.78
 - -
0.83
 --

Substrate: AOF2 (demethylase)
Seq-ID: Q6ZQ88 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription repressor activity,
histone demethylase activity (H3-K9 specific),
ligand-dependent nuclear receptor transcription coactivator activity,
androgen receptor binding,
chromatin binding,
oxidoreductase activity,
histone demethylase activity (H3-dimethyl-K4 specific),
FAD binding,
promoter binding,
sequence-specific DNA binding transcription factor activity		 transcription factor complex negative regulation of gene-specific transcription from RNA polymerase II promoter,
negative regulation of transcription factor activity,
transcription,
oxidation reduction,
regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor,
in utero embryonic development,
pituitary gland development,
positive regulation of transcription from RNA polymerase II promoter,
cell proliferation,
positive regulation of hormone biosynthetic process
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 167 PQAPPEEENESEPEEPSGVEG - 19144319
HTP
1.00
 - -
0.97
 --

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