Substrate: APC8 (Cell cycle control protein)
Seq-ID: Q8BGZ4 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
binding anaphase-promoting complex cell division,
protein K11-linked ubiquitination,
mitosis,
regulation of mitotic metaphase/anaphase transition
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 562 QILQLRNQGETPTSDTPGTFF - 15345747
HTP
0.71
 - -
0.46
 - medium
S 578 PGTFFLPASLSANNTPTRRVS - 15345747
HTP
0.11
 - -
0.39
 - medium
S 588 SANNTPTRRVSPLNLSSVTP  - 17242355
HTP
0.22
 - -
0.52
 - medium
T 596 RVSPLNLSSVTP          - 17242355
HTP
0.44
 - -
0.31
 - medium

Substrate: APC8 (Cell cycle control protein)
Seq-ID: Q9UJX2 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-66993   RBPMS_HUMAN
MINT-67439   T22D4_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
binding,
ubiquitin-protein ligase activity		 cytosol,
anaphase-promoting complex,
nucleoplasm		 cell division,
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,
G1 phase of mitotic cell cycle,
protein K11-linked ubiquitination,
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,
mitotic metaphase/anaphase transition,
regulation of exit from mitosis,
mitotic metaphase plate congression,
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process,
regulation of mitotic metaphase/anaphase transition
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 267 SYIVSQIAVAYHNIRDIDKAL - 14657031
HTP
0.00
 - TPR
0.02
 - medium
T 556 QILQLRNQGETPTTEVPAPFF CDK1 14657031
LTP
0.00
 - -
0.39
 - medium
T 556 QILQLRNQGETPTTEVPAPFF PLK1 14657031
LTP
0.00
 - -
0.39
 - medium
T 556 QILQLRNQGETPTTEVPAPFF - 14657031
HTP
0.00
 - -
0.39
 - medium
T 556 QILQLRNQGETPTTEVPAPFF - 18669648
HTP
0.00
 - -
0.39
 - medium
T 556 QILQLRNQGETPTTEVPAPFF - 22067460
HTP
0.00
 - -
0.39
 - medium
T 558 LQLRNQGETPTTEVPAPFFLP - 18669648
HTP
0.44
 - -
0.39
 - medium
T 559 QLRNQGETPTTEVPAPFFLPA - 14657031
LTP
0.83
 - -
0.39
 - medium
T 559 QLRNQGETPTTEVPAPFFLPA - 14657031
HTP
0.83
 - -
0.39
 - medium
T 559 QLRNQGETPTTEVPAPFFLPA - 18669648
HTP
0.83
 - -
0.39
 - medium
S 570 EVPAPFFLPASLSANNTPTRR - 18669648
HTP
0.77
 - -
0.38
 - medium
S 570 EVPAPFFLPASLSANNTPTRR - 22067460
HTP
0.77
 - -
0.38
 - medium
S 572 PAPFFLPASLSANNTPTRRVS - 18669648
HTP
0.24
 - -
0.34
 - medium
S 572 PAPFFLPASLSANNTPTRRVS - 22067460
HTP
0.24
 - -
0.34
 - medium
T 576 FLPASLSANNTPTRRVSPLNL CDK1 14657031
HTP
0.65
 MOD_CDK_SPxK_1
 - -
0.36
 - medium
T 576 FLPASLSANNTPTRRVSPLNL - 18669648
HTP
0.65
 MOD_CDK_SPxK_1
 - -
0.36
 - medium
T 576 FLPASLSANNTPTRRVSPLNL - 22067460
HTP
0.65
 MOD_CDK_SPxK_1
 - -
0.36
 - medium
T 578 PASLSANNTPTRRVSPLNLSS - 18669648
HTP
0.63
 - -
0.40
 - medium
T 578 PASLSANNTPTRRVSPLNLSS - 22067460
HTP
0.63
 - -
0.40
 - medium
S 582 SANNTPTRRVSPLNLSSVTP  - 15302935
HTP
0.89
 - -
0.50
 - medium
S 582 SANNTPTRRVSPLNLSSVTP  - 17081983
HTP
0.89
 - -
0.50
 - medium
S 582 SANNTPTRRVSPLNLSSVTP  - 16964243
HTP
0.89
 - -
0.50
 - medium
S 582 SANNTPTRRVSPLNLSSVTP  - 18669648
HTP
0.89
 - -
0.50
 - medium
S 582 SANNTPTRRVSPLNLSSVTP  - 22067460
HTP
0.89
 - -
0.50
 - medium
S 587 PTRRVSPLNLSSVTP       - 17081983
HTP
0.00
 - -
0.47
 - medium
S 587 PTRRVSPLNLSSVTP       - 18669648
HTP
0.00
 - -
0.47
 - medium
S 587 PTRRVSPLNLSSVTP       - 22067460
HTP
0.00
 - -
0.47
 - medium
S 588 TRRVSPLNLSSVTP        - 18669648
HTP
1.00
 - -
0.44
 - medium
S 588 TRRVSPLNLSSVTP        - 22067460
HTP
1.00
 - -
0.44
 - medium
T 590 RVSPLNLSSVTP          - 16565220
HTP
0.69
 - -
0.29
 - medium
T 590 RVSPLNLSSVTP          - 17081983
HTP
0.69
 - -
0.29
 - medium
T 590 RVSPLNLSSVTP          - 16964243
HTP
0.69
 - -
0.29
 - medium
T 590 RVSPLNLSSVTP          - 18669648
HTP
0.69
 - -
0.29
 - medium
T 590 RVSPLNLSSVTP          - 22067460
HTP
0.69
 - -
0.29
 - medium

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