Substrate: AT1AR (G protein coupled receptor)
Seq-ID: P30556 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
MINT-4791905   ARRB1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
acetyltransferase activator activity,
angiotensin type II receptor activity,
protein heterodimerization activity,
bradykinin receptor binding,
angiotensin type I receptor activity		 integral to plasma membrane elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger,
regulation of cell growth,
calcium-mediated signaling,
regulation of vasoconstriction,
Rho protein signal transduction,
kidney development,
low-density lipoprotein particle remodeling,
regulation of vasodilation,
positive regulation of macrophage derived foam cell differentiation,
regulation of natriuresis,
positive regulation of NAD(P)H oxidase activity,
positive regulation of phospholipase A2 activity,
positive regulation of inflammatory response,
regulation of blood vessel size by renin-angiotensin,
oxygen and reactive oxygen species metabolic process,
regulation of cell proliferation,
renin-angiotensin regulation of aldosterone production,
cell chemotaxis,
positive regulation of cellular protein metabolic process,
positive regulation of cholesterol esterification
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 319 FKRYFLQLLKYIPPKAKSHSN - 12522132
LTP
0.05
 JAK2 SH2;
PLCG1 SH2;
PTPN11 SH2		 -
0.03
 - medium

Valid HTML 4.01 Transitional