Substrate: BAX (protein binding)
Seq-ID: Q07812 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-17572   1433S_HUMAN
MINT-7034069   B2L11_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein heterodimerization activity,
protein homodimerization activity,
lipid binding,
BH3 domain binding		 cytosol,
mitochondrial outer membrane,
endoplasmic reticulum membrane,
mitochondrial permeability transition pore complex		 B cell apoptosis,
induction of apoptosis by extracellular signals,
establishment or maintenance of transmembrane electrochemical gradient,
mitochondrial fragmentation involved in apoptosis,
positive regulation of neuron apoptosis,
regulation of protein homodimerization activity,
response to toxin,
activation of caspase activity by cytochrome c,
release of cytochrome c from mitochondria,
regulation of mitochondrial membrane potential,
nuclear fragmentation involved in apoptotic nuclear change,
negative regulation of survival gene product expression,
regulation of protein heterodimerization activity,
induction of apoptosis by intracellular signals,
cleavage of lamin,
induction of retinal programmed cell death,
protein homooligomerization,
DNA fragmentation involved in apoptotic nuclear change,
transformed cell apoptosis,
mitochondrial fusion,
release of matrix enzymes from mitochondria
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 184 TIFVAGVLTASLTIWKKMG   - 15642728
LTP
0.03
 - TRANS
0.01
 --

Substrate: BAX (protein binding)
Seq-ID: Q07813 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
MINT-13682   VDAC1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein heterodimerization activity,
protein homodimerization activity,
BH3 domain binding		 integral to membrane,
soluble fraction,
endoplasmic reticulum,
cytosolic part,
mitochondrial outer membrane		 positive regulation of apoptosis involved in mammary gland involution,
negative regulation of fibroblast proliferation,
response to salt stress,
positive regulation of neuron apoptosis,
positive regulation of release of sequestered calcium ion into cytosol,
response to toxin,
blood vessel remodeling,
positive regulation of B cell apoptosis,
fertilization,
kidney development,
nuclear fragmentation involved in apoptotic nuclear change,
hypothalamus development,
B cell homeostasis,
negative regulation of peptidyl-serine phosphorylation,
negative regulation of anti-apoptosis,
myeloid cell homeostasis,
odontogenesis of dentine-containing tooth,
development of secondary sexual characteristics,
protein homooligomerization,
glycosphingolipid metabolic process,
B cell homeostatic proliferation,
mitochondrial fusion,
B cell apoptosis,
retinal cell programmed cell death,
protein insertion into mitochondrial membrane involved in induction of apoptosis,
cellular response to UV,
homeostasis of number of cells within a tissue,
positive regulation of developmental pigmentation,
regulation of cell cycle,
reduction of endoplasmic reticulum calcium ion concentration,
regulation of mammary gland epithelial cell proliferation,
germ cell programmed cell death,
activation of caspase activity by cytochrome c,
release of cytochrome c from mitochondria,
germ cell development,
response to axon injury,
spermatid differentiation,
B cell negative selection,
induction of apoptosis in response to chemical stimulus,
regulation of mitochondrial membrane permeability,
response to gamma radiation,
vagina development,
neuron migration,
retina development in camera-type eye,
induction of apoptosis by intracellular signals,
apoptosis in response to endoplasmic reticulum stress,
neuron apoptosis,
post-embryonic camera-type eye morphogenesis,
negative regulation of neuron apoptosis,
Sertoli cell proliferation,
T cell homeostatic proliferation,
response to DNA damage stimulus,
regulation of nitrogen utilization,
limb morphogenesis,
cerebral cortex development,
ovarian follicle development,
response to acid
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 184 TIFVAGVLTASLTIWKKMG   PKB_group 14766748
LTP
0.04
 - TRANS
0.01
 - low

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