Substrate: Beta-catenin (Adhesion molecule)
Seq-ID: P35222 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-46005   CADH1_HUMAN
MINT-46006   CTNA1_HUMAN
MINT-49803   ANDR_HUMAN
MINT-49805   NCOA2_HUMAN
MINT-1779698   TF7L2_HUMAN
MINT-1792780   LAP2_HUMAN
MINT-1792796   PKP4_HUMAN
MINT-2839028   LAP2B_HUMAN
MINT-2839079   EMD_HUMAN
MINT-4085223   CADH5_HUMAN
MINT-4085261   PARD3_HUMAN
MINT-4085491   CADH2_HUMAN
MINT-4508051   GSK3B_HUMAN
MINT-4508065   ITF2_HUMAN
MINT-4508192   AXN1_HUMAN
MINT-4508216   ABL1_HUMAN
MINT-4508229   APC_HUMAN
MINT-6823807   HDAC1_HUMAN
MINT-7023862   NFKB1_HUMAN
MINT-7952417   TNIK_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
R-SMAD binding,
cadherin binding,
androgen receptor binding,
alpha-catenin binding,
kinase binding,
protein phosphatase binding,
transcription coactivator activity,
promoter binding,
signal transducer activity,
estrogen receptor binding,
I-SMAD binding,
protein C-terminus binding		 Axin-APC-beta-catenin-GSK3B complex,
catenin complex,
transcription factor complex,
perinuclear region of cytoplasm,
cell cortex,
protein-DNA complex,
beta-catenin-TCF7L2 complex,
centrosome,
cell-substrate adherens junction,
lateral plasma membrane		 positive regulation of gene-specific transcription from RNA polymerase II promoter,
patterning of blood vessels,
protein localization at cell surface,
positive regulation of heparan sulfate proteoglycan biosynthetic process,
negative regulation of cell proliferation,
cellular response to indole-3-methanol,
response to drug,
positive regulation of anti-apoptosis,
positive regulation of apoptosis,
canonical Wnt receptor signaling pathway,
regulation of calcium ion import,
androgen receptor signaling pathway,
adherens junction assembly,
regulation of fibroblast proliferation,
epithelial to mesenchymal transition,
regulation of smooth muscle cell proliferation,
cell-cell adhesion,
cellular response to growth factor stimulus,
positive regulation of epithelial to mesenchymal transition,
regulation of angiogenesis,
endothelial tube morphogenesis,
negative regulation of apoptosis,
transcription,
regulation of centriole-centriole cohesion,
regulation of centromeric sister chromatid cohesion,
response to estradiol stimulus
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 33 SHWQQQSYLDSGIHSGATTTA GSK-3_group 12051714
LTP
0.30
 MOD_GSK3_1
 - -
0.58
 --
S 37 QQSYLDSGIHSGATTTAPSLS GSK-3_group 12051714
LTP
0.96
 MOD_GSK3_1
 - -
0.62
 --
T 41 LDSGIHSGATTTAPSLSGKGN GSK-3_group 12051714
LTP
0.90
 MOD_GSK3_1
 - -
0.75
 --
S 45 IHSGATTTAPSLSGKGNPEEE CK1_group 12000790
LTP
0.80
 - -
0.88
 --
Y 86 QEQVADIDGQYAMTRAQRVRA SRC 11279024
LTP
0.18
 - -
0.45
 --
T 102 QRVRAAMFPETLDEGMQIPST CK2_group 12432063
LTP
0.95
 MOD_CK2_1
 - -
0.53
 --
T 112 TLDEGMQIPSTQFDAAHPTNV CK2_group 12432063
LTP
0.92
 - -
0.68
 --
Y 142 LKHAVVNLINYQDDAELATRA Fyn 12640114
LTP
0.94
 - ARM
0.32
 1G3J 74.24%
T 393 WTLRNLSDAATKQEGMEGLLG CK2_group 12700239
LTP
0.95
 MOD_CK2_1
 - ARM
0.24
 1JDH 34.25%
T 551 VRAHQDTQRRTSMGGTQQQFV - 18220336
HTP
0.12
 - ARM
0.58
 1QZ7 56.85%
S 552 RAHQDTQRRTSMGGTQQQFVE - 18220336
HTP
0.83
 YWHAB 14-3-3 ARM
0.57
 1QZ7 72.95%
S 552 RAHQDTQRRTSMGGTQQQFVE - 18669648
HTP
0.83
 YWHAB 14-3-3 ARM
0.57
 1QZ7 72.95%
T 556 DTQRRTSMGGTQQQFVEGVRM - 18220336
HTP
0.30
 - ARM
0.54
 1QZ7 67.81%
T 556 DTQRRTSMGGTQQQFVEGVRM - 18669648
HTP
0.30
 - ARM
0.54
 1QZ7 67.81%
Y 654 LHSRNEGVATYAAAVLFRMSE SRC 11279024
LTP
0.98
 - ARM
0.28
 1JDH 25.76%
S 675 DKPQDYKKRLSVELTSSLFRT - 17081983
HTP
1.00
 - -
0.43
 2Z6H 36.89%
S 675 DKPQDYKKRLSVELTSSLFRT - 18220336
HTP
1.00
 - -
0.43
 2Z6H 36.89%

Substrate: Beta-catenin (Adhesion molecule)
Seq-ID: Q02248 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19635   P85A_MOUSE
MINT-24866   TF7L2_HUMAN
MINT-45999   FER_HUMAN
MINT-46000   FYN_HUMAN
MINT-46001   YES_HUMAN
MINT-46002   SRC_HUMAN
MINT-46007   CTNA1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cadherin binding,
alpha-catenin binding,
chromatin binding,
promoter binding,
transcription repressor binding,
specific RNA polymerase II transcription factor activity,
double-stranded DNA binding,
protein phosphatase binding,
transcription coactivator activity,
sequence-specific DNA binding transcription factor activity		 basolateral plasma membrane,
centrosome,
membrane fraction,
apical junction complex,
lamellipodium,
lateral plasma membrane,
microvillus membrane,
Z disc,
Axin-APC-beta-catenin-GSK3B complex,
transcription factor complex,
fascia adherens,
apical part of cell		 branching involved in ureteric bud morphogenesis,
positive regulation of mesenchymal cell proliferation,
dorsal/ventral axis specification,
patterning of blood vessels,
smooth muscle cell differentiation,
anterior/posterior axis specification,
cellular response to organic cyclic substance,
embryonic axis specification,
glial cell fate determination,
sensory perception of taste,
cell maturation,
synaptic vesicle transport,
cell-matrix adhesion,
lung-associated mesenchyme development,
embryonic hindlimb morphogenesis,
cell fate specification,
synaptic transmission,
epithelial tube branching involved in lung morphogenesis,
odontogenesis of dentine-containing tooth,
positive regulation of osteoblast differentiation,
embryonic arm morphogenesis,
regulation of T cell proliferation,
cell-cell adhesion,
cellular protein localization,
forebrain development,
renal inner medulla development,
embryonic foregut morphogenesis,
negative regulation of apoptosis,
transcription,
positive regulation of I-kappaB kinase/NF-kappaB cascade,
renal vesicle formation,
gastrulation with mouth forming second,
nephron tubule formation,
positive regulation of branching involved in lung morphogenesis,
regulation of centromeric sister chromatid cohesion,
thymus development,
proximal/distal pattern formation,
embryonic heart tube development,
epithelial cell differentiation involved in prostate gland development,
mesenchymal to epithelial transition involved in metanephros morphogenesis,
morphogenesis of embryonic epithelium,
skeletal system development,
in utero embryonic development,
lung induction,
canonical Wnt receptor signaling pathway,
camera-type eye morphogenesis,
endodermal cell fate commitment,
genitalia morphogenesis,
synapse organization,
renal outer medulla development,
positive regulation of epithelial cell proliferation involved in prostate gland development,
male genitalia development,
negative regulation of chondrocyte differentiation,
negative regulation of osteoclast differentiation,
T cell differentiation in the thymus,
tongue morphogenesis,
negative regulation of transcription from RNA polymerase II promoter,
oocyte development,
pancreas development,
hair follicle placode formation,
osteoclast differentiation,
positive regulation of MAPKKK cascade,
hair follicle morphogenesis,
positive regulation of fibroblast growth factor receptor signaling pathway,
apoptosis,
central nervous system vasculogenesis,
mesenchymal cell proliferation involved in lung development,
trachea formation,
positive regulation of endothelial cell differentiation,
lung cell differentiation,
bone resorption,
embryonic digit morphogenesis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 551 VRAHQDTQRRTSMGGTQQQFV - 17242355
HTP
0.12
 - ARM
0.58
 1QZ7 56.85%
T 551 VRAHQDTQRRTSMGGTQQQFV - 17114649
HTP
0.12
 - ARM
0.58
 1QZ7 56.85%
S 552 RAHQDTQRRTSMGGTQQQFVE - 17242355
HTP
0.83
 - ARM
0.57
 1QZ7 72.95%
T 556 DTQRRTSMGGTQQQFVEGVRM - 17242355
HTP
0.30
 - ARM
0.54
 1QZ7 67.81%
T 556 DTQRRTSMGGTQQQFVEGVRM - 17114649
HTP
0.30
 - ARM
0.54
 1QZ7 67.81%

Substrate: Beta-catenin (Adhesion molecule)
Seq-ID: Q9WU82 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
MINT-61574   FYN_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ionotropic glutamate receptor binding,
cadherin binding,
protein complex binding		 dendritic shaft,
synapse		 transcription,
response to estrogen stimulus,
response to organic cyclic substance,
response to cytokine stimulus,
myoblast differentiation,
Schwann cell proliferation,
liver development,
odontogenesis of dentine-containing tooth,
protein heterooligomerization,
response to cadmium ion,
cell-cell adhesion,
midgut development
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 191 KEASRHAIMRSPQMVSAIVRT - 16396499
HTP
0.96
 - ARM
0.39
 1JDH 25.41%
S 675 DKPQDYKKRLSVELTSSLFRT - 16396499
HTP
1.00
 - -
0.43
 2Z6H 36.89%

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