Substrate: CD44 (CD antigen)
Seq-ID: A2APM6 [Mus musculus]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
hyaluronic acid binding external side of plasma membrane,
basolateral plasma membrane		 branching involved in ureteric bud morphogenesis,
branching involved in prostate gland morphogenesis,
wound healing involved in inflammatory response,
cell adhesion,
positive regulation of gene expression
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 452 KKLVINGGNGTVEDRKPSELN - 19144319
HTP
0.32
 - -
0.68
 - medium
S 459 GNGTVEDRKPSELNGEASKSQ - 19144319
HTP
1.00
 - -
0.81
 - medium
S 468 PSELNGEASKSQEMVHLVNKE - 19144319
HTP
1.00
 - -
0.71
 - medium
S 497 MTADETRNLQSVDMKIGV    - 19144319
HTP
0.32
 - -
0.44
 - medium

Substrate: CD44 (CD antigen)
Seq-ID: P16070 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor activity,
collagen binding,
receptor signaling protein activity,
hyaluronic acid binding		 integral to plasma membrane positive regulation of peptidyl-tyrosine phosphorylation,
positive regulation of ERK1 and ERK2 cascade,
negative regulation of apoptosis,
positive regulation of peptidyl-serine phosphorylation,
negative regulation of DNA damage response, signal transduction by p53 class mediator,
cell-matrix adhesion,
cell-cell adhesion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 45 HVEKNGRYSISRTEAADLCKA - 18669648
HTP
1.00
 - LINK
0.16
 1UUH 16.39%
S 58 EAADLCKAFNSTLPTMAQMEK - 18669648
HTP
1.00
 - LINK
0.18
 1UUH 9.02%
T 62 LCKAFNSTLPTMAQMEKALSI - 18669648
HTP
1.00
 - LINK
0.14
 1UUH 30.82%
S 291 ENEDERDRHLSFSGSGIDDDE PKC_group 12032545
LTP
1.00
 - -
0.78
 --
S 672 LILAVCIAVNSRRRCGQKKKL PKC_alpha 12032545
LTP
1.00
 - TRANS
0.23
 --
S 686 CGQKKKLVINSGNGAVEDRKP - 17081983
HTP
0.13
 - -
0.60
 --
S 686 CGQKKKLVINSGNGAVEDRKP - 18669648
HTP
0.13
 - -
0.60
 --
S 697 GNGAVEDRKPSGLNGEASKSQ - 17081983
HTP
1.00
 - -
0.79
 --
S 697 GNGAVEDRKPSGLNGEASKSQ - 18669648
HTP
1.00
 - -
0.79
 --
S 706 PSGLNGEASKSQEMVHLVNKE - 12032545
LTP
1.00
 - -
0.69
 --
S 706 PSGLNGEASKSQEMVHLVNKE - 17081983
HTP
1.00
 - -
0.69
 --
S 706 PSGLNGEASKSQEMVHLVNKE - 18669648
HTP
1.00
 - -
0.69
 --
T 720 VHLVNKESSETPDQFMTADET - 17081983
HTP
1.00
 - -
0.69
 --
T 720 VHLVNKESSETPDQFMTADET - 18669648
HTP
1.00
 - -
0.69
 --

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