Substrate: DUSP6 (protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity)
Seq-ID: Q16828 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein tyrosine phosphatase activity,
MAP kinase tyrosine/serine/threonine phosphatase activity		 cytoplasm,
nucleoplasm		 inactivation of MAPK activity,
peptidyl-tyrosine dephosphorylation,
positive regulation of apoptosis,
response to nitrosative stress,
negative regulation of ERK1 and ERK2 cascade
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 159 TNLDGSCSSSSPPLPVLGLGG MAPK1 15632084
LTP
1.00
 MOD_ProDKin_1
 - -
0.37
 --
S 159 TNLDGSCSSSSPPLPVLGLGG MAPK3 15632084
LTP
1.00
 MOD_ProDKin_1
 - -
0.37
 --
S 328 DAYDIVKMKKSNISPNFNFMG - 18220336
HTP
1.00
 - DSPc
0.16
 1MKP 82.79%
S 331 DIVKMKKSNISPNFNFMGQLL - 18220336
HTP
1.00
 - DSPc
0.14
 1MKP 85.25%
S 331 DIVKMKKSNISPNFNFMGQLL - 18669648
HTP
1.00
 - DSPc
0.14
 1MKP 85.25%

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