Phospho.ELM Result

a database of S/T/Y phosphorylation sites

E-cadherin (Epithelial-cadherin precursor (E-cadherin) (Uvomorulin) (Cadherin-1) (CAM 120/80))

Seq-ID:

P09803 [Mus musculus]

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Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
calcium ion binding, protein domain specific binding, beta-catenin binding, protein phosphatase binding, RPTP-like protein binding	cell-cell adherens junction, basolateral plasma membrane, integral to membrane, apical part of cell	protein metabolic process, trophectodermal cell differentiation, protein homooligomerization, regulation of branching involved in salivary gland morphogenesis, salivary gland cavitation, homophilic cell adhesion, regulation of caspase activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	755	PPDDDTRDNVYYYDEEGGGEE	-	11836526	LTP	0.19		-	Cadherin_C	0.70	-	-
Y	756	PDDDTRDNVYYYDEEGGGEED	-	11836526	LTP	1.00		-	Cadherin_C	0.71	-	-
S	840	DSLLVFDYEGSGSEAASLSSL	CK2_alpha	10671552	LTP	1.00	MOD_CK2_1	-	Cadherin_C	0.47	1I7W	99.18%
S	849	GSGSEAASLSSLNSSESDQDQ	GSK-3_group	10671552	LTP	1.00	MOD_GSK3_1	-	Cadherin_C	0.83	1I7W	103.28%
S	853	EAASLSSLNSSESDQDQDYDY	CK2_alpha	10671552	LTP	1.00		-	Cadherin_C	0.73	-	-
S	855	ASLSSLNSSESDQDQDYDYLN	CK2_alpha	10671552	LTP	1.00		-	Cadherin_C	0.68	-	-

E-cadherin (Epithelial-cadherin precursor (E-cadherin) (Uvomorulin) (Cadherin-1) (CAM 120/80))

Seq-ID:

P12830 [Homo sapiens]

Download:

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription activator activity, beta-catenin binding, cell adhesion molecule binding, gamma-catenin binding	cell-cell adherens junction, apical junction complex, catenin complex, lateral plasma membrane, integral to membrane, perinuclear region of cytoplasm, actin cytoskeleton	cellular response to indole-3-methanol, positive regulation of transcription factor import into nucleus, cellular response to lithium ion, homophilic cell adhesion

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	844	DYEGSGSEAASLSSLNSSESD	CK1_delta	17353278	LTP	0.98	MOD_CK1_1	-	Cadherin_C	0.71	-	low
S	851	EAASLSSLNSSESDKDQDYDY	CK2_group	10671552	LTP	1.00		-	Cadherin_C	0.67	-	low