Substrate: ERCC3 (3' to 5' DNA helicase activity, damaged DNA binding)
Seq-ID: P19447 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein C-terminus binding,
ATP binding,
damaged DNA binding,
transcription factor binding,
protein N-terminus binding,
3`-5` DNA helicase activity		 holo TFIIH complex hair cell differentiation,
nucleotide-excision repair, DNA incision,
response to oxidative stress,
nucleotide-excision repair, DNA damage removal,
DNA topological change,
nucleotide-excision repair, DNA duplex unwinding,
interspecies interaction between organisms,
transcription initiation from RNA polymerase II promoter,
RNA elongation from RNA polymerase II promoter,
induction of apoptosis,
positive regulation of transcription from RNA polymerase II promoter,
cell cycle checkpoint,
protein localization,
transcription-coupled nucleotide-excision repair
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 370 RCLVLGNSAVSVEQWKAQFKM - 17081983
HTP
0.96
 - DEXDc
0.09
 - medium
S 751 SRRFGTMSSMSGADDTVYMEY CK2_alpha 15549133
LTP
0.98
 - -
0.39
 - medium

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