Substrate: Eif2ak1 (Eukaryotic translation initiation factor)
Seq-ID: Q9Z2R9 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
eukaryotic translation initiation factor 2alpha kinase activity,
protein homodimerization activity,
heme binding,
ATP binding		 cytoplasm regulation of eIF2 alpha phosphorylation by heme,
response to stress,
negative regulation of cell proliferation,
negative regulation of translation,
protein amino acid autophosphorylation,
protoporphyrinogen IX metabolic process,
response to external stimulus,
negative regulation of hemoglobin biosynthetic process
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 483 WTNRNGKGTRTHTSRVGTCLY - 12767237
LTP
0.06
 - STYKc
0.47
 - medium
T 485 NRNGKGTRTHTSRVGTCLYAS - 12767237
LTP
1.00
 - STYKc
0.46
 - medium
T 490 GTRTHTSRVGTCLYASPEQLE - 12767237
LTP
1.00
 - STYKc
0.43
 - medium

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