Substrate: FGFR-3 (Receptor tyrosine kinase)
Seq-ID: P22607 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
identical protein binding,
fibroblast growth factor binding,
fibroblast growth factor receptor activity,
ATP binding		 integral to plasma membrane positive regulation of cell proliferation,
protein amino acid phosphorylation,
MAPKKK cascade,
cell growth,
JAK-STAT cascade,
skeletal system development
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 444 NTPLVRIARLSSGEGPTLANV - 18669648
HTP
0.78
 - -
0.35
 - medium
S 445 TPLVRIARLSSGEGPTLANVS - 18669648
HTP
0.87
 - -
0.33
 - medium
T 450 IARLSSGEGPTLANVSELELP - 18669648
HTP
0.04
 - -
0.37
 - medium
Y 577 LRARRPPGLDYSFDTCKPPEE FGFR3 11294897
LTP
0.99
 - TyrKc
0.42
 - medium
Y 647 GLARDVHNLDYYKKTTNGRLP FGFR3 11294897
LTP
1.00
 - TyrKc
0.22
 - medium
Y 648 LARDVHNLDYYKKTTNGRLPV FGFR3 11294897
LTP
1.00
 - TyrKc
0.21
 - medium
Y 724 DKPANCTHDLYMIMRECWHAA FGFR3 11294897
LTP
1.00
 GRB2 SH2;
SHC1 SH2		 TyrKc
0.23
 - medium
Y 760 RVLTVTSTDEYLDLSAPFEQY FGFR3 11294897
LTP
0.95
 PLCG1 SH2 -
0.33
 - medium
Y 770 YLDLSAPFEQYSPGGQDTPSS FGFR3 11294897
LTP
0.96
 - -
0.60
 - medium

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