Substrate: Gab1 (Multisubstrate docking protein downstream in the signaling pathways of different RTK.)
Seq-ID: Q13480 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 242 MNGFFQQQMIYDSPPSRAPSA INSR 10978177
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2
-
0.65
- low
Y 259 APSASVDSSLYNLPRSYSHDV - 12522270
HTP
0.15
CRKL SH2;
CRK SH2
-
0.59
- low
S 266 SSLYNLPRSYSHDVLPKVSPS - 12522270
HTP
0.19
- -
0.58
- low
Y 285 PSSTEADGELYVFNTPSGTSS - 10978177
LTP
0.93
- -
0.71
- low
Y 285 PSSTEADGELYVFNTPSGTSS EGFR 9890893
LTP
0.93
- -
0.71
- low
Y 285 PSSTEADGELYVFNTPSGTSS Met 10734310
LTP
0.93
- -
0.71
- low
Y 307 ETQMRHVSISYDIPPTPGNTY Met 10734310
LTP
0.12
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2
-
0.70
- low
Y 307 ETQMRHVSISYDIPPTPGNTY EGFR 10734310
LTP
0.12
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2
-
0.70
- low
Y 317 YDIPPTPGNTYQIPRTFPEGT - 16497976
HTP
0.24
CRKL SH2;
CRK SH2;
PLCG1 SH2;
RASA_group SH2
-
0.74
- low
Y 373 PRTASDTDSSYCIPTAGMSPS INSR 10978177
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 373 PRTASDTDSSYCIPTAGMSPS EGFR 9890893
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 373 PRTASDTDSSYCIPTAGMSPS - 10753869
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 373 PRTASDTDSSYCIPTAGMSPS Met 10734310
LTP
0.08
CRKL SH2;
CRK SH2;
PLCG1 SH2
-
0.66
- low
Y 406 LRKDASSQDCYDIPRAFPSDR EGFR 9890893
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low
Y 406 LRKDASSQDCYDIPRAFPSDR - 10753869
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low
Y 406 LRKDASSQDCYDIPRAFPSDR Met 10734310
LTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low
Y 406 LRKDASSQDCYDIPRAFPSDR - 18083107
HTP
1.00
CRKL SH2;
CRK SH2;
NCK SH2;
PLCG1 SH2;
SHC_group SH2
-
0.61
- low
Y 447 SVSSEELDENYVPMNPNSPPR INSR 10978177
LTP
1.00
PIK3R1 SH2;
PIK3R2 SH2;
PTPN11 SH2
-
0.83
- low
Y 447 SVSSEELDENYVPMNPNSPPR EGFR 9890893
LTP
1.00
PIK3R1 SH2;
PIK3R2 SH2;
PTPN11 SH2
-
0.83
- low
Y 447 SVSSEELDENYVPMNPNSPPR Met 10734310
LTP
1.00
PIK3R1 SH2;
PIK3R2 SH2;
PTPN11 SH2
-
0.83
- low
Y 472 SFTEPIQEANYVPMTPGTFDF INSR 10978177
LTP
1.00
PIK3R1 SH2;
PIK3R2 SH2
-
0.54
- low
Y 472 SFTEPIQEANYVPMTPGTFDF EGFR 9890893
LTP
1.00
PIK3R1 SH2;
PIK3R2 SH2
-
0.54
- low
Y 472 SFTEPIQEANYVPMTPGTFDF Met 10734310
LTP
1.00
PIK3R1 SH2;
PIK3R2 SH2
-
0.54
- low
T 476 PIQEANYVPMTPGTFDFSSFG MAPK1 15379552
LTP
0.18
MOD_ProDKin_1
- -
0.50
- low
Y 589 SSDSHDSEENYVPMNPNLSSE INSR 10978177
LTP
1.00
PIK3R1 SH2;
PTPN11 SH2
-
0.89
- low
Y 589 SSDSHDSEENYVPMNPNLSSE EGFR 9890893
LTP
1.00
PIK3R1 SH2;
PTPN11 SH2
-
0.89
- low
Y 589 SSDSHDSEENYVPMNPNLSSE Met 10734310
LTP
1.00
PIK3R1 SH2;
PTPN11 SH2
-
0.89
- low
Y 627 IKPKGDKQVEYLDLDLDSGKS INSR 10978177
LTP
1.00
PTPN11 SH2 -
0.72
- low
Y 627 IKPKGDKQVEYLDLDLDSGKS EGFR 9890893
LTP
1.00
PTPN11 SH2 -
0.72
- low
Y 627 IKPKGDKQVEYLDLDLDSGKS Met 10734310
LTP
1.00
PTPN11 SH2 -
0.72
- low
Y 627 IKPKGDKQVEYLDLDLDSGKS - 18083107
HTP
1.00
PTPN11 SH2 -
0.72
- low
Y 659 GSSVADERVDYVVVDQQKTLA - 10978177
LTP
1.00
PTPN11 SH2 -
0.61
- low
Y 659 GSSVADERVDYVVVDQQKTLA EGFR 9890893
LTP
1.00
PTPN11 SH2 -
0.61
- low
Y 659 GSSVADERVDYVVVDQQKTLA Met 10734310
LTP
1.00
PTPN11 SH2 -
0.61
- low
Y 659 GSSVADERVDYVVVDQQKTLA - 18083107
HTP
1.00
PTPN11 SH2 -
0.61
- low
Y 659 GSSVADERVDYVVVDQQKTLA - 18669648
HTP
1.00
PTPN11 SH2 -
0.61
- low

Substrate: Gab1 (Multisubstrate docking protein downstream in the signaling pathways of different RTK.)
Seq-ID: Q9QYY0 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 285 PSSTEADGELYTFNTPSGTAG Met 10734310
LTP
0.93
- -
0.77
- medium
Y 285 PSSTEADGELYTFNTPSGTAG EGFR 10734310
LTP
0.93
- -
0.77
- medium
Y 307 ETQMRHVSISYDIPPTPGNTY Met 10734310
LTP
0.12
- -
0.71
- medium
Y 307 ETQMRHVSISYDIPPTPGNTY EGFR 10734310
LTP
0.12
- -
0.71
- medium
Y 373 PRTASDTDSSYCIPPPAGMTP Met 10734310
LTP
0.08
- -
0.75
- medium
Y 373 PRTASDTDSSYCIPPPAGMTP EGFR 10734310
LTP
0.08
- -
0.75
- medium
Y 407 LRKDASSQDCYDIPRTFPSDR Met 10734310
LTP
1.00
- -
0.66
- medium
Y 407 LRKDASSQDCYDIPRTFPSDR EGFR 10734310
LTP
1.00
- -
0.66
- medium
Y 448 GVSGEELDENYVPMNPNSPPR Met 10734310
LTP
1.00
- -
0.87
- medium
Y 448 GVSGEELDENYVPMNPNSPPR EGFR 10734310
LTP
1.00
- -
0.87
- medium
Y 473 SFTEPIQEPNYVPMTPGTFDF Met 10734310
LTP
1.00
- -
0.61
- medium
Y 473 SFTEPIQEPNYVPMTPGTFDF EGFR 10734310
LTP
1.00
- -
0.61
- medium
Y 473 SFTEPIQEPNYVPMTPGTFDF - 11896055
LTP
1.00
- -
0.61
- medium
T 477 PIQEPNYVPMTPGTFDFSSFG - 11896055
LTP
0.17
- -
0.56
- medium
T 504 AHMGFRSSPKTPPRRPVPVAD - 17242355
HTP
1.00
- -
0.81
- medium
Y 590 SSDSHDSEENYVPMNPNLSGE Met 10734310
LTP
1.00
- -
0.90
- medium
Y 590 SSDSHDSEENYVPMNPNLSGE EGFR 10734310
LTP
1.00
- -
0.90
- medium
Y 628 NKPKGDKQVEYLDLDLDSGKS Met 10734310
LTP
1.00
- -
0.78
- medium
Y 628 NKPKGDKQVEYLDLDLDSGKS EGFR 10734310
LTP
1.00
- -
0.78
- medium
Y 660 GSSMADERVDYVVVDQQKTLA Met 10734310
LTP
1.00
- -
0.68
- medium
Y 660 GSSMADERVDYVVVDQQKTLA EGFR 10734310
LTP
1.00
- -
0.68
- medium

Valid HTML 4.01 Transitional