Substrate: Grb10 (Adapter molecule)
Seq-ID: Q13322 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-15644   IGF1R_HUMAN
MINT-16516   INSR_HUMAN
MINT-16802   EGFR_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
insulin receptor binding,
SH3/SH2 adaptor activity		 plasma membrane,
cytoplasm		 negative regulation of glycogen biosynthetic process,
negative regulation of insulin receptor signaling pathway,
negative regulation of glucose import,
positive regulation of vascular endothelial growth factor receptor signaling pathway,
negative regulation of Wnt receptor signaling pathway,
insulin receptor signaling pathway,
positive regulation of phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 67 NDMNASLESLYSACSMQSDTV Fyn 10871840
LTP
0.81
 Fyn SH2;
Src SH2		 -
0.50
 - low
Y 67 NDMNASLESLYSACSMQSDTV SRC 10871840
LTP
0.81
 Fyn SH2;
Src SH2		 -
0.50
 - low
S 104 GPPRSIQPQVSPRQRVQRSQP - 16964243
HTP
0.59
 - -
0.82
 - low
S 104 GPPRSIQPQVSPRQRVQRSQP - 18669648
HTP
0.59
 - -
0.82
 - low
S 150 NPFPELCGPGSPPVLTPGSLP MAPK1 15952796
LTP
0.71
 MOD_ProDKin_1
 - -
0.65
 - low
S 150 NPFPELCGPGSPPVLTPGSLP MAPK3 15952796
LTP
0.71
 MOD_ProDKin_1
 - -
0.65
 - low
Y 404 FRLLKYGMLLYQNYRIPQQRK - 18083107
HTP
0.92
 - -
0.13
 - low
S 418 RIPQQRKALLSPFSTPVRSVS - 18220336
HTP
0.67
 - -
0.43
 - low
S 418 RIPQQRKALLSPFSTPVRSVS - 18669648
HTP
0.67
 - -
0.43
 - low
S 421 QQRKALLSPFSTPVRSVSENS - 18669648
HTP
0.82
 - -
0.40
 - low
T 422 QRKALLSPFSTPVRSVSENSL - 18669648
HTP
0.47
 - -
0.38
 - low
S 476 STRMNILGSQSPLHPSTLSTV MAPK1 15952796
LTP
0.89
 MOD_ProDKin_1
 - -
0.42
 - low
S 476 STRMNILGSQSPLHPSTLSTV MAPK3 15952796
LTP
0.89
 MOD_ProDKin_1
 - -
0.42
 - low
S 476 STRMNILGSQSPLHPSTLSTV - 18669648
HTP
0.89
 MOD_ProDKin_1
 - -
0.42
 - low

Substrate: Grb10 (Adapter molecule)
Seq-ID: Q60760 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-51135   PERQ2_MOUSE
MINT-73463   INSR_MOUSE
MINT-73466   INSR_HUMAN
MINT-73467   IGF1R_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
insulin receptor binding,
SH3/SH2 adaptor activity,
phosphotyrosine binding		 cytosol negative regulation of glycogen biosynthetic process,
negative regulation of insulin receptor signaling pathway,
negative regulation of glucose import,
insulin-like growth factor receptor signaling pathway,
positive regulation of vascular endothelial growth factor receptor signaling pathway,
negative regulation of Wnt receptor signaling pathway,
negative regulation of phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 96 FPELTGAAPGSPPSVAPSSLP - 15345747
HTP
0.91
 - -
0.89
 - low
S 455 PPFNAPMRSVSENSLVAMDFS PKB_group 15722337
LTP
1.00
 - BPS
0.37
 - low
S 458 NAPMRSVSENSLVAMDFSGQI - 17242355
HTP
1.00
 - BPS
0.33
 - low

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