Substrate: HDAC7A (Enzyme: Deacetylase)
Seq-ID: Q8C2B3 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19703   MEF2C_MOUSE
MINT-3089136   NCOR2_MOUSE
MINT-3089169   MEF2A_MOUSE
MINT-3089216   1433E_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
specific transcriptional repressor activity,
histone deacetylase activity,
transcription corepressor activity,
chromatin binding		 histone deacetylase complex,
cytoplasm		 B cell differentiation,
nervous system development,
chromatin modification,
transcription,
negative regulation of striated muscle tissue development,
inflammatory response,
vasculogenesis,
cell-cell junction assembly,
negative regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 344 GLHRPLNRTRSEPLPPSATAS - 17242355
HTP
1.00
 - -
0.88
 - low

Substrate: HDAC7A (Enzyme: Deacetylase)
Seq-ID: Q8WUI4 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-3296507   1433Z_HUMAN
MINT-3975829   1433S_HUMAN
MINT-6177417   KPCD2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase C binding,
transcription repressor binding,
histone deacetylase activity		 histone deacetylase complex,
cytoplasm		 negative regulation of interleukin-2 production,
chromatin modification,
transcription,
positive regulation of cell migration involved in sprouting angiogenesis,
negative regulation of osteoblast differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 109 AALERTVHPNSPGIPYRTLEP - 18669648
HTP
1.00
 - -
0.73
 - medium
Y 114 TVHPNSPGIPYRTLEPLETEG - 18220336
HTP
0.90
 - -
0.79
 - medium
S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 15623513
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.63
 - medium
S 155 PEHFPLRKTVSEPNLKLRYKP MARK_group 16980613
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.63
 - medium
S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 18617643
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.63
 - medium
S 155 PEHFPLRKTVSEPNLKLRYKP PKD1 18509061
LTP
1.00
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.63
 - medium
S 283 TLGPRGPILGSPHTPLFLPHG - 18669648
HTP
0.68
 - -
0.70
 - medium
T 286 PRGPILGSPHTPLFLPHGLEP - 18669648
HTP
0.10
 - -
0.69
 - medium
T 356 GSGLHWPLSRTRSEPLPPSAT - 18669648
HTP
1.00
 - -
0.80
 - medium
S 358 GLHWPLSRTRSEPLPPSATAP - 15623513
LTP
1.00
 - -
0.85
 - medium
S 358 GLHWPLSRTRSEPLPPSATAP - 18669648
HTP
1.00
 - -
0.85
 - medium
S 486 GGHRPLSRAQSSPAAPASLSA - 15302935
HTP
1.00
 - -
0.84
 - medium
S 486 GGHRPLSRAQSSPAAPASLSA - 18669648
HTP
1.00
 - -
0.84
 - medium
S 487 GHRPLSRAQSSPAAPASLSAP - 15302935
HTP
1.00
 - -
0.85
 - medium
S 487 GHRPLSRAQSSPAAPASLSAP - 18669648
HTP
1.00
 - -
0.85
 - medium

Valid HTML 4.01 Transitional