Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

HNF4-alpha (Nuclear receptor)

Seq-ID:

P41235 [Homo sapiens]

Download:

Interaction Network(s):

NetworKIN

External Source(s):

Phosida

MINT Interaction(s):

MINT-16696 SRBP2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein homodimerization activity, fatty acid binding, zinc ion binding, promoter binding, receptor binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity	cytoplasm, nucleus	regulation of growth hormone receptor signaling pathway, positive regulation of gene-specific transcription from RNA polymerase II promoter, transcription, blood coagulation, negative regulation of cell proliferation, negative regulation of cell growth, lipid homeostasis, regulation of lipid metabolic process, ornithine metabolic process, xenobiotic metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	142	NERDRISTRRSSYEDSSLPSI	-	16351573	LTP	0.61		-	-	0.45	-	-
S	143	ERDRISTRRSSYEDSSLPSIN	-	16351573	LTP	0.71		-	-	0.42	-	-
S	167	QAEVLSRQITSPVSGINGDIR	MAPK11	16351573	LTP	0.39	MOD_ProDKin_1	-	-	0.27	-	-
S	190	KIASIADVCESMKEQLLVLVE	-	16351573	LTP	1.00		-	HOLI	0.05	1PZL	4.10%
S	313	SDPGKIKRLRSQVQVSLEDYI	AMPK_group	12740371	LTP	0.14		-	HOLI	0.28	1PZL	42.62%
T	469	PLSAIPQPTITKQEVI	-	16351573	LTP	0.30		-	-	0.59	-	-

HNF4-alpha (Nuclear receptor)

Seq-ID:

P49698 [Mus musculus]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription activator binding, transcription activator activity, RNA polymerase II transcription factor activity, enhancer binding, zinc ion binding, promoter binding, steroid hormone receptor activity		lipid metabolic process, positive regulation of gene-specific transcription from RNA polymerase II promoter, transcription, glucose homeostasis, response to glucose stimulus, SMAD protein signal transduction, regulation of gastrulation, regulation of insulin secretion, sex differentiation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	429	EWPRPRGQAATPETPQPSPPS	-	17242355	HTP	0.02		-	-	0.94	-	medium
T	432	RPRGQAATPETPQPSPPSGSG	-	17242355	HTP	0.80		-	-	0.96	-	medium