Substrate: HSPA1A (unfolded protein binding)
Seq-ID: P08107 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-13841   AIFM1_HUMAN
MINT-14029   APAF_HUMAN
MINT-16428   APEX1_HUMAN
MINT-17370   KSR1_MOUSE
MINT-50346   1433B_HUMAN
MINT-50358   1433Z_HUMAN
MINT-50363   1433T_HUMAN
MINT-72641   HS90B_HUMAN
MINT-2791462   RD23A_HUMAN
MINT-2859843   ATX1_HUMAN
MINT-2871494   HPBP1_HUMAN
MINT-7555062   SYUA_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ubiquitin protein ligase binding,
protein binding involved in protein folding,
unfolded protein binding,
ATP binding,
protein N-terminus binding		 inclusion body,
mitochondrion,
ribonucleoprotein complex,
nuclear speck,
perinuclear region of cytoplasm,
endoplasmic reticulum		 response to unfolded protein,
mRNA catabolic process,
negative regulation of cell proliferation,
negative regulation of cell growth,
anti-apoptosis,
protein refolding,
negative regulation of inclusion body assembly
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 41 NDQGNRTTPSYVAFTDTERLI - 18083107
HTP
0.97
 - HSP70
0.44
 2E8A 2.62%
S 362 DFFNGRDLNKSINPDEAVAYG - 18669648
HTP
1.00
 - HSP70
0.29
 2E8A 89.34%
Y 371 KSINPDEAVAYGAAVQAAILM - 18669648
HTP
1.00
 - HSP70
0.21
 2E8A 30.13%
Y 525 IERMVQEAEKYKAEDEVQRER - 10843914
LTP
0.92
 - COIL
0.57
 --
Y 611 QVCNPIISGLYQGAGGPGPGG - 17287340
HTP
0.97
 - HSP70
0.50
 --
S 631 GFGAQGPKGGSGSGPTIEEVD - 17081983
HTP
0.18
 - -
0.76
 --
S 631 GFGAQGPKGGSGSGPTIEEVD - 16964243
HTP
0.18
 - -
0.76
 --

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