Substrate: IRAK3 (ser/thr kinase)
Seq-ID: Q8K4B2 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
magnesium ion binding,
protein serine/threonine kinase activity,
ATP binding		 cytoplasm,
nucleus		 negative regulation of MAP kinase activity,
negative regulation of protein catabolic process,
negative regulation of tumor necrosis factor production,
negative regulation of innate immune response,
negative regulation of toll-like receptor signaling pathway,
response to peptidoglycan,
response to exogenous dsRNA,
protein amino acid autophosphorylation,
positive regulation of NF-kappaB transcription factor activity,
negative regulation of interleukin-12 production,
response to lipopolysaccharide,
interleukin-1-mediated signaling pathway,
negative regulation of macrophage cytokine production,
negative regulation of interleukin-6 production,
negative regulation of cytokine-mediated signaling pathway,
positive regulation of macrophage tolerance induction,
response to virus
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 601 EKRCSSGLFCSEHEQSKKQ   - 17203969
HTP
0.61
 - -
0.41
 - medium

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