Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

JAK1 (Cytoplasmic tyrosine kinase)

Seq-ID:

P23458 [Homo sapiens]

Download:

Interaction Network(s):

NetworKIN

External Source(s):

Phosida

Phosida

MINT Interaction(s):

[show]

MINT-15831   STAM2_HUMAN
MINT-16582   BRCA1_HUMAN
MINT-74561   ERBB2_HUMAN
MINT-2729859   INAR2_HUMAN
MINT-4507294   KPCA_HUMAN
MINT-7974754   DLG4_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Janus kinase activity, non-membrane spanning protein tyrosine kinase activity, ATP binding, growth hormone receptor binding	cytoplasm, cytoskeleton, nucleus, membrane, endomembrane system	response to antibiotic

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	208	ELPKDISYKRYIPETLNKSIR	-	15659558	HTP	0.00		-	B41	0.33	-	-
Y	1022	LTKAIETDKEYYTVKDDRDSP	JAK3	12559972	LTP	0.00		-	TyrKc	0.29	3EYG	61.14%
Y	1022	LTKAIETDKEYYTVKDDRDSP	-	15659558	LTP	0.00		-	TyrKc	0.29	3EYG	61.14%
Y	1022	LTKAIETDKEYYTVKDDRDSP	-	15659558	HTP	0.00		-	TyrKc	0.29	3EYG	61.14%
Y	1023	TKAIETDKEYYTVKDDRDSPV	JAK3	12559972	LTP	0.00		-	TyrKc	0.27	3EYG	45.85%
Y	1023	TKAIETDKEYYTVKDDRDSPV	-	15659558	LTP	0.00		-	TyrKc	0.27	3EYG	45.85%
Y	1023	TKAIETDKEYYTVKDDRDSPV	-	15659558	HTP	0.00		-	TyrKc	0.27	3EYG	45.85%

JAK1 (Cytoplasmic tyrosine kinase)

Seq-ID:

P52332 [Mus musculus]

Download:

Interaction Network(s):

-

External Source(s):

Phosida

MINT Interaction(s):

MINT-13640 PTPRC_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Janus kinase activity, non-membrane spanning protein tyrosine kinase activity, ATP binding, growth hormone receptor binding	cytoskeleton, membrane, endomembrane system	cytokine-mediated signaling pathway, enzyme linked receptor protein signaling pathway, peptidyl-tyrosine phosphorylation, intracellular protein kinase cascade

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	1033	LTKAIETDKEYYTVKDDRDSP	-	15923602	LTP	1.00		-	TyrKc	0.27	-	low
Y	1033	LTKAIETDKEYYTVKDDRDSP	-	14557412	LTP	1.00		-	TyrKc	0.27	-	low
Y	1034	TKAIETDKEYYTVKDDRDSPV	-	15923602	LTP	1.00		-	TyrKc	0.25	-	low
Y	1034	TKAIETDKEYYTVKDDRDSPV	-	14557412	LTP	1.00		-	TyrKc	0.25	-	low