Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Ku70 (DNA repair protein)

Seq-ID:

P12956 [Homo sapiens]

Download:

Interaction Network(s):

NetworKIN

External Source(s):

Phosida

Phosida

MINT Interaction(s):

[show]

MINT-60809   Z512B_HUMAN
MINT-61696   SMAD3_HUMAN
MINT-63311   FMNL_HUMAN
MINT-63409   RLA1_HUMAN
MINT-63486   PECA1_HUMAN
MINT-63718   VATE1_HUMAN
MINT-63953   RRAS2_HUMAN
MINT-63980   1433Z_HUMAN
MINT-64134   SNTA1_HUMAN
MINT-65113   ACD_HUMAN
MINT-65145   CDCA5_HUMAN
MINT-65245   ARAP1_HUMAN
MINT-65249   CRML_HUMAN
MINT-73060   WBP4_HUMAN
MINT-3978316   HD_HUMAN
MINT-3979927   CLH1_HUMAN
MINT-4051792   KU86_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATP-dependent DNA helicase activity, 5`-deoxyribose-5-phosphate lyase activity, protein C-terminus binding, transcription activator activity, double-stranded DNA binding, ATP binding, promoter binding	membrane fraction, Ku70:Ku80 complex, nuclear telomere cap complex, transcription factor complex, DNA-dependent protein kinase-DNA ligase 4 complex	double-strand break repair via nonhomologous end joining, provirus integration, positive regulation of gene-specific transcription from RNA polymerase II promoter, DNA ligation, telomere maintenance, initiation of viral infection

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	6	MSGWESYYKTEGDEEA	-	10026262	LTP	0.10		-	-	0.50	-	-
S	6	MSGWESYYKTEGDEEA	-	15941674	LTP	0.10		-	-	0.50	-	-
S	37	SGDYKYSGRDSLIFLVDASKA	-	15302935	HTP	1.00		-	Ku_N	0.16	1JEQ	0.00%
S	222	DISLFYRDIISIAEDEDLRVH	-	16097034	HTP	0.93		-	Ku_N	0.07	1JEQ	17.21%

Ku70 (DNA repair protein)

Seq-ID:

P23475 [Mus musculus]

Download:

Interaction Network(s):

-

External Source(s):

Phosida

Phosida

MINT Interaction(s):

MINT-2568431 TAL1_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
ATP-dependent DNA helicase activity, 5`-deoxyribose-5-phosphate lyase activity, ATP binding	Ku70:Ku80 complex, cytoplasm, chromosome, DNA-dependent protein kinase-DNA ligase 4 complex	double-strand break repair via nonhomologous end joining, positive regulation of neurogenesis, response to ionizing radiation, V(D)J recombination

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	6	MSEWESYYKTEGEEEE	-	10026262	LTP	0.04		-	-	0.61	-	medium