Substrate: LckBP1 (Hematopoietic cell-specific LYN substrate 1)
Seq-ID: P14317 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-61343   LYN_HUMAN
MINT-67768   SH24A_HUMAN
MINT-7971786   DLG4_RAT
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding transcription factor activity mitochondrion,
nucleus,
membrane		 intracellular signaling pathway,
positive regulation of cell proliferation,
response to hormone stimulus,
erythrocyte differentiation,
positive regulation of tyrosine phosphorylation of STAT protein,
regulation of transcription, DNA-dependent
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 103 RMDKSAVGHEYVAEVEKHSSQ - 16094384
HTP
1.00
 - HS1_rep
0.62
 - medium
Y 198 RDYAKGFGGQYGIQKDRVDKS - 12522270
HTP
1.00
 - HS1_rep
0.50
 - medium
Y 198 RDYAKGFGGQYGIQKDRVDKS - 15144186
HTP
1.00
 - HS1_rep
0.50
 - medium
Y 222 FNEMEAPTTAYKKTTPIEAAS Lyn 10066823
LTP
1.00
 - HS1_rep
0.68
 - medium
Y 222 FNEMEAPTTAYKKTTPIEAAS Fgr 10066823
LTP
1.00
 - HS1_rep
0.68
 - medium
S 275 QQERKAVTKRSPEAPQPVIAM - 16094384
HTP
0.26
 - -
0.85
 - medium
Y 360 EGLQVEEEPVYEAEPEPEPEP - 8578591
LTP
0.94
 - -
0.96
 - medium
Y 378 PEPEPEPENDYEDVEEMDRHE - 8578591
LTP
0.18
 Lyn SH2 -
0.98
 - medium
Y 378 PEPEPEPENDYEDVEEMDRHE Lyn 9104825
LTP
0.18
 Lyn SH2 -
0.98
 - medium
Y 378 PEPEPEPENDYEDVEEMDRHE SYK 9104825
LTP
0.18
 Lyn SH2 -
0.98
 - medium
Y 397 HEQEDEPEGDYEEVLEPEDSS - 8578591
LTP
0.80
 Lyn SH2 -
0.95
 - medium
Y 397 HEQEDEPEGDYEEVLEPEDSS Fgr 9183008
LTP
0.80
 Lyn SH2 -
0.95
 - medium
Y 397 HEQEDEPEGDYEEVLEPEDSS Lyn 9104825
LTP
0.80
 Lyn SH2 -
0.95
 - medium
Y 397 HEQEDEPEGDYEEVLEPEDSS SYK 9104825
LTP
0.80
 Lyn SH2 -
0.95
 - medium

Substrate: LckBP1 (Hematopoietic cell-specific LYN substrate 1)
Seq-ID: P49710 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-58758   LYN_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
protein complex binding		 mitochondrion,
nucleus		 positive regulation of cell proliferation,
response to hormone stimulus,
erythrocyte differentiation,
positive regulation of tyrosine phosphorylation of STAT protein
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 388 YEPEPETEPDYEDVGELDRQD - 15166239
LTP
0.17
 - -
0.97
 - medium
Y 405 DRQDEDAEGDYEDVLEPEDTP - 15166239
LTP
0.06
 - -
0.95
 - medium

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