Substrate: MAP3K3 (Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.1.-) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)
Seq-ID: Q61084 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
metal ion binding,
ATP binding,
MAP kinase kinase kinase activity,
protein binding		 protein amino acid phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 337 QYLDPRGRLRSADSENALTVQ - 17242355
HTP
0.46
 - -
0.54
 - medium
S 340 DPRGRLRSADSENALTVQERN - 17242355
HTP
0.12
 - -
0.61
 - medium
S 526 TICMSGTGIRSVTGTPYWMSP - 16407301
LTP
1.00
 - S_TKc
0.25
 - medium

Substrate: MAP3K3 (Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.1.-) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)
Seq-ID: Q99759 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-16168   M3K5_HUMAN
MINT-48367   BAG2_HUMAN
MINT-48368   AIFM1_HUMAN
MINT-48370   RPAP3_HUMAN
MINT-48371   NEMO_HUMAN
MINT-48373   HS71L_HUMAN
MINT-48374   HSP74_HUMAN
MINT-48375   TCPQ_HUMAN
MINT-48377   GRP78_HUMAN
MINT-48378   DREB_HUMAN
MINT-48379   DNJB4_HUMAN
MINT-48380   HSP7C_HUMAN
MINT-48381   TMOD3_HUMAN
MINT-48382   IKKA_HUMAN
MINT-48384   UBL4A_HUMAN
MINT-48389   ADT2_HUMAN
MINT-48390   HSP72_HUMAN
MINT-48392   GRP75_HUMAN
MINT-48393   SYMC_HUMAN
MINT-48394   COR1C_HUMAN
MINT-48395   RUVB2_HUMAN
MINT-48396   SUGT1_HUMAN
MINT-48397   IQGA1_HUMAN
MINT-48399   MYO1C_HUMAN
MINT-48402   EPIPL_HUMAN
MINT-48403   SERA_HUMAN
MINT-48406   DNJA1_HUMAN
MINT-48407   CDC37_HUMAN
MINT-48408   SYIC_HUMAN
MINT-48410   ACTN4_HUMAN
MINT-48411   HNRH1_HUMAN
MINT-48413   C1QBP_HUMAN
MINT-48414   EF1A2_HUMAN
MINT-48416   SPTA2_HUMAN
MINT-48417   PFD4_HUMAN
MINT-48420   MATR3_HUMAN
MINT-48421   1433T_HUMAN
MINT-48422   TCPA_HUMAN
MINT-48425   MYH10_HUMAN
MINT-48426   PYR1_HUMAN
MINT-48428   ACTG_HUMAN
MINT-48430   TERA_HUMAN
MINT-48433   CLH1_HUMAN
MINT-48434   IKKB_HUMAN
MINT-48435   STUB1_HUMAN
MINT-48437   GNAI2_HUMAN
MINT-48444   PP1A_HUMAN
MINT-48449   F10A1_HUMAN
MINT-48451   TBB6_HUMAN
MINT-48453   NUDC_HUMAN
MINT-48456   CALM_HUMAN
MINT-48458   TFG_HUMAN
MINT-48461   FAS_HUMAN
MINT-48462   TBB5_HUMAN
MINT-48463   K6PL_HUMAN
MINT-48464   TBB3_HUMAN
MINT-48467   TBB4_HUMAN
MINT-48468   RS27_HUMAN
MINT-48469   K1967_HUMAN
MINT-48470   MPRIP_HUMAN
MINT-48472   SCRIB_HUMAN
MINT-48474   UACA_HUMAN
MINT-48475   RAI14_HUMAN
MINT-48476   TRAF7_HUMAN
MINT-48477   ALK_HUMAN
MINT-48478   DNJA3_HUMAN
MINT-48479   M3K2_HUMAN
MINT-48480   1433Z_HUMAN
MINT-48481   FLNA_HUMAN
MINT-48483   MYPT1_HUMAN
MINT-48484   MARK2_HUMAN
MINT-48485   MYH9_HUMAN
MINT-48486   LYN_HUMAN
MINT-48488   SMRC2_HUMAN
MINT-48490   VIME_HUMAN
MINT-48491   1433B_HUMAN
MINT-48492   1433F_HUMAN
MINT-48494   H4_HUMAN
MINT-48495   SPTB2_HUMAN
MINT-48496   ADT3_HUMAN
MINT-48497   HS90A_HUMAN
MINT-48499   F10A4_HUMAN
MINT-48500   PYGM_HUMAN
MINT-48501   PP1G_HUMAN
MINT-48504   PRKDC_HUMAN
MINT-48505   MYL6_HUMAN
MINT-48506   DLG1_HUMAN
MINT-48508   G3P_HUMAN
MINT-48510   SC16A_HUMAN
MINT-48511   MP2K5_HUMAN
MINT-48513   COF2_HUMAN
MINT-48514   AKP8L_HUMAN
MINT-48516   DNJC7_HUMAN
MINT-48519   LIMA1_HUMAN
MINT-48520   HS90B_HUMAN
MINT-48521   ML12A_HUMAN
MINT-48522   GNAI3_HUMAN
MINT-48527   MYO1D_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
metal ion binding,
ATP binding,
MAP kinase kinase kinase activity,
protein binding		 positive regulation of I-kappaB kinase/NF-kappaB cascade,
MAPKKK cascade,
protein amino acid autophosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 166 QPPEPRSRHLSVSSQNPGRSS - 12392720
LTP
0.83
 - -
0.90
 - medium
S 166 QPPEPRSRHLSVSSQNPGRSS SGK_group 12761204
LTP
0.83
 - -
0.90
 - medium
S 166 QPPEPRSRHLSVSSQNPGRSS - 18220336
HTP
0.83
 - -
0.90
 - medium
S 337 QYLDPRGRLRSADSENALSVQ - 12392720
LTP
0.83
 - -
0.53
 - medium
S 337 QYLDPRGRLRSADSENALSVQ SGK_group 12761204
LTP
0.83
 - -
0.53
 - medium

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