Substrate: Merlin (Probably acts as a ,15, stabilizing protein)
Seq-ID: P35240 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cytoskeletal protein binding early endosome,
cytoskeleton,
nucleolus,
ruffle membrane,
extrinsic to membrane,
perinuclear region of cytoplasm,
filopodium membrane		 negative regulation of DNA replication,
actin cytoskeleton organization,
negative regulation of tyrosine phosphorylation of Stat5 protein,
positive regulation of stress fiber assembly,
negative regulation of cell proliferation,
regulation of hippo signaling cascade,
negative regulation of cell-matrix adhesion,
Schwann cell proliferation,
negative regulation of cell-cell adhesion,
negative regulation of cell migration,
negative regulation of tyrosine phosphorylation of Stat3 protein
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 518 DFKDTDMKRLSMEIEKEKVEY PAK_group 11719502
LTP
1.00
 MOD_PKA_1
 - COIL
0.46
 - medium
S 518 DFKDTDMKRLSMEIEKEKVEY PKA_group 14981079
LTP
1.00
 MOD_PKA_1
 - COIL
0.46
 - medium
S 518 DFKDTDMKRLSMEIEKEKVEY - 11782491
LTP
1.00
 MOD_PKA_1
 - COIL
0.46
 - medium
S 518 DFKDTDMKRLSMEIEKEKVEY PAK2 15378014
LTP
1.00
 MOD_PKA_1
 - COIL
0.46
 - medium
S 518 DFKDTDMKRLSMEIEKEKVEY - 17081983
HTP
1.00
 MOD_PKA_1
 - COIL
0.46
 - medium
S 518 DFKDTDMKRLSMEIEKEKVEY - 18669648
HTP
1.00
 MOD_PKA_1
 - COIL
0.46
 - medium

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