Substrate: NPR-A (Guanylate cyclase)
Seq-ID: P16066 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
MINT-61913   MCAF1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
GTP binding,
guanylate cyclase activity,
ATP binding,
peptide receptor activity, G-protein coupled,
protein kinase activity,
natriuretic peptide receptor activity		 integral to plasma membrane regulation of blood vessel size,
protein amino acid phosphorylation,
diuresis,
receptor guanylyl cyclase signaling pathway,
negative regulation of angiogenesis,
regulation of blood pressure,
negative regulation of cell growth,
natriuresis,
regulation of vasodilation,
regulation of vascular permeability
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 529 SLERHLRSAGSRLTLSGRGSN PKA_group 9528788
LTP
1.00
 MOD_PKA_2
 - STYKc
0.37
 - medium
T 532 RHLRSAGSRLTLSGRGSNYGS - 9528788
LTP
1.00
 - STYKc
0.31
 - medium
S 534 LRSAGSRLTLSGRGSNYGSLL - 9528788
LTP
1.00
 - STYKc
0.31
 - medium
S 538 GSRLTLSGRGSNYGSLLTTEG - 9528788
LTP
1.00
 - STYKc
0.30
 - medium
S 542 TLSGRGSNYGSLLTTEGQFQV - 9528788
LTP
1.00
 - STYKc
0.22
 - medium
T 545 GRGSNYGSLLTTEGQFQVFAK - 9528788
LTP
1.00
 - STYKc
0.17
 - medium

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