Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Nefl (Neurofilament protein L)

Seq-ID:

P02548 [Bos taurus]

Download:

Interaction Network(s):

STRING

External Source(s):

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein C-terminus binding, identical protein binding, structural constituent of cytoskeleton	neurofilament	locomotion, anterograde axon cargo transport, axon regeneration in the peripheral nervous system, positive regulation of axonogenesis, negative regulation of neuron apoptosis, regulation of axon diameter, neurofilament bundle assembly, axon transport of mitochondrion, neuromuscular process controlling balance, retrograde axon cargo transport, microtubule cytoskeleton organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	27	RYVETPRVHISSVRSGYSTAR	ROCK_group	9571164	LTP	0.27		-	Filament_head	0.40	-	medium
S	58	SSSLSVRRSYSSSSGSLMPSL	ROCK_group	9571164	LTP	0.13		-	Filament_head	0.40	-	medium

Nefl (Neurofilament protein L)

Seq-ID:

P07196 [Homo sapiens]

Download:

Interaction Network(s):

External Source(s):

Phosida

MINT Interaction(s):

[show]

MINT-65251   CK5P2_HUMAN
MINT-3980097   CHD3_HUMAN
MINT-3980114   BRD7_HUMAN
MINT-3980318   VIME_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein C-terminus binding, identical protein binding, structural constituent of cytoskeleton	neurofilament, cytosol	anterograde axon cargo transport, neurofilament bundle assembly, axon transport of mitochondrion, retrograde axon cargo transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	472	KAEEAKDEPPSEGEAEEEEKD	-	17287340	HTP	0.03		-	COIL	0.97	-	low

Nefl (Neurofilament protein L)

Seq-ID:

P08551 [Mus musculus]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	neurofilament	locomotion, axon regeneration in the peripheral nervous system, positive regulation of axonogenesis, negative regulation of neuron apoptosis, regulation of axon diameter, neuromuscular process controlling balance, microtubule cytoskeleton organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	58	SSSLSVRRSYSSSSGSLMPSL	-	10854283	LTP	0.18		-	Filament_head	0.41	-	low
S	473	KAEEAKDEPPSEGEAEEEEKE	-	16452087	HTP	0.04		-	COIL	0.97	-	low
S	532	ESEEEEKKEESAGEEQVAKKK	-	16452087	HTP	0.77		-	-	0.89	-	low