Substrate: PAX6 (Transcription factor)
Seq-ID: P26367 [Homo sapiens]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):
MINT-7974222   DLG4_RAT
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
sequence-specific DNA binding transcription factor activity,
protein binding		 cytoplasm,
nucleus		 central nervous system development,
transcription,
organ morphogenesis,
eye development,
neuron fate commitment,
response to wounding,
visual perception,
regulation of transcription, DNA-dependent
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 216 LKRKLQRNRTSFTQEQIEALE - 18669648
HTP
1.00
 - COIL
0.56
 --

Substrate: PAX6 (Transcription factor)
Seq-ID: P63015 [Mus musculus]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
promoter binding,
sequence-specific DNA binding transcription factor activity,
protein binding		 transcription factor complex axon guidance,
dorsal/ventral axis specification,
transcription,
regulation of cell migration,
astrocyte differentiation,
keratinocyte differentiation,
negative regulation of epithelial cell proliferation,
protein localization in organelle,
regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification,
eye photoreceptor cell development,
regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification,
positive regulation of neuroblast proliferation,
forebrain anterior/posterior pattern formation,
oligodendrocyte cell fate specification,
forebrain-midbrain boundary formation,
smoothened signaling pathway,
negative regulation of neuron differentiation,
regulation of timing of cell differentiation,
positive regulation of epithelial cell differentiation,
neuron migration,
forebrain dorsal/ventral pattern formation,
pallium development,
commitment of a neuronal cell to a specific type of neuron in the forebrain,
cell fate determination,
pituitary gland development,
positive regulation of transcription from RNA polymerase II promoter,
regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment,
lacrimal gland development,
lens development in camera-type eye,
salivary gland morphogenesis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 281 LRNQRRQASNTPSHIPISSSF HIPK2 16407227
LTP
0.13
 - -
0.75
 --
T 304 SVYQPIPQPTTPVSSFTSGSM HIPK2 16407227
LTP
0.25
 - -
0.63
 --
T 373 SVNGRSYDTYTPPHMQTHMNS HIPK2 16407227
LTP
0.26
 - -
0.77
 --

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