Substrate: Ref1 (NA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP endonuclease 1) (APEX nuclease) (APEN) (REF-1 protein))
Seq-ID: P27695 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-16428   HSP71_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
phosphodiesterase I activity,
DNA binding,
endodeoxyribonuclease activity,
metal ion binding,
3`-5` exonuclease activity,
transcription corepressor activity,
oxidoreductase activity,
uracil DNA N-glycosylase activity,
ribonuclease H activity,
DNA-(apurinic or apyrimidinic site) lyase activity,
transcription coactivator activity		 centrosome,
ribosome,
nucleoplasm,
perinuclear region of cytoplasm,
endoplasmic reticulum		 transcription from RNA polymerase II promoter,
base-excision repair,
regulation of DNA binding
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 290 WRLDYFLLSHSLLPALCDSKI CK2_group 10023679
LTP
0.29
 - Exo_endo_phos
0.03
 2O3H 67.21%

Valid HTML 4.01 Transitional