Substrate: SFN (protein binding, protein kinase C inhibitor activity)
Seq-ID: P31947 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14116   GCR_HUMAN
MINT-15829   CDC2_HUMAN
MINT-17572   BAX_HUMAN
MINT-17710   TSC2_HUMAN
MINT-51069   MPIP2_HUMAN
MINT-66103   BAD_HUMAN
MINT-66436   PKHF2_HUMAN
MINT-66797   PLK4_HUMAN
MINT-2983605   KAP2_HUMAN
MINT-3319979   1433Z_HUMAN
MINT-3974750   ABLM1_HUMAN
MINT-3974770   SHRM1_HUMAN
MINT-3974833   RHGBA_HUMAN
MINT-3974844   RHG21_HUMAN
MINT-3974900   ARHGH_HUMAN
MINT-3974919   ARHGG_HUMAN
MINT-3974941   BCAR1_HUMAN
MINT-3974952   CING_HUMAN
MINT-3974974   GAN_HUMAN
MINT-3974985   GRB7_HUMAN
MINT-3975007   LAD1_HUMAN
MINT-3975066   MARK1_HUMAN
MINT-3975077   MARK2_HUMAN
MINT-3975099   PAK4_HUMAN
MINT-3975110   PAR3L_HUMAN
MINT-3975121   PARD3_HUMAN
MINT-3975132   PKP2_HUMAN
MINT-3975156   PKP3_HUMAN
MINT-3975167   LIPB1_HUMAN
MINT-3975178   LIPB2_HUMAN
MINT-3975189   PTN3_HUMAN
MINT-3975200   RGAP1_HUMAN
MINT-3975242   RHPN2_HUMAN
MINT-3975290   SHRM3_HUMAN
MINT-3975301   SI1L1_HUMAN
MINT-3975312   SI1L3_HUMAN
MINT-3975342   ZO2_HUMAN
MINT-3975353   APC_HUMAN
MINT-3975364   ARAF_HUMAN
MINT-3975375   BRAF_HUMAN
MINT-3975386   RAF1_HUMAN
MINT-3975397   CSK21_HUMAN
MINT-3975408   DTX2_HUMAN
MINT-3975419   DYR1A_HUMAN
MINT-3975430   IRS1_HUMAN
MINT-3975441   IRS2_HUMAN
MINT-3975452   M3K2_HUMAN
MINT-3975485   SIN1_HUMAN
MINT-3975507   OSBL3_HUMAN
MINT-3975518   P3C2B_HUMAN
MINT-3975529   PI4KB_HUMAN
MINT-3975555   PPR3D_HUMAN
MINT-3975592   PTN2_HUMAN
MINT-3975603   SASH1_HUMAN
MINT-3975614   SH23A_HUMAN
MINT-3975625   SH3B4_HUMAN
MINT-3975636   SHCBP_HUMAN
MINT-3975647   ST5_HUMAN
MINT-3975686   TNK1_HUMAN
MINT-3975697   JUB_HUMAN
MINT-3975708   KIF23_HUMAN
MINT-3975719   MARK3_HUMAN
MINT-3975741   WEE1_HUMAN
MINT-3975752   MLTK_HUMAN
MINT-3975807   UBP8_HUMAN
MINT-3975818   HDAC4_HUMAN
MINT-3975829   HDAC7_HUMAN
MINT-3975864   ZN638_HUMAN
MINT-3975875   MYCB2_HUMAN
MINT-3975886   TRI32_HUMAN
MINT-3975897   KINH_HUMAN
MINT-3975908   KLC2_HUMAN
MINT-3976028   KLC1_HUMAN
MINT-3976039   CYH2_HUMAN
MINT-3976105   SYNJ2_HUMAN
MINT-3976116   SF13A_HUMAN
MINT-3976127   HNRPU_HUMAN
MINT-3976138   SRRM2_HUMAN
MINT-3976149   ISCU_HUMAN
MINT-3976160   ANS1A_HUMAN
MINT-3976193   LMO7_HUMAN
MINT-3976316   MPRIP_HUMAN
MINT-3976327   SG223_HUMAN
MINT-3976338   EDC3_HUMAN
MINT-3976408   REEP4_HUMAN
MINT-3976446   UBP43_HUMAN
MINT-3976465   F117B_HUMAN
MINT-3976484   FA53B_HUMAN
MINT-3976506   PACS2_HUMAN
MINT-3976629   REEP3_HUMAN
MINT-3976640   PDZ11_HUMAN
MINT-3976660   RICTR_HUMAN
MINT-3976701   ERRFI_HUMAN
MINT-7711943   P53_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein domain specific binding,
protein kinase C inhibitor activity		 cytoplasm,
extracellular space,
nucleus		 negative regulation of caspase activity,
release of cytochrome c from mitochondria,
signal transduction,
negative regulation of protein kinase activity,
DNA damage response, signal transduction resulting in induction of apoptosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 186 FSVFHYEIANSPEEAISLAKT MAPK8 15071501
LTP
0.79
 MOD_ProDKin_1
 - 14_3_3
0.25
 1YWT 17.21%
S 248 EGGEAPQEPQS           - 16964243
HTP
0.13
 - -
0.56
 --
S 248 EGGEAPQEPQS           - 18669648
HTP
0.13
 - -
0.56
 --

Substrate: SFN (protein binding, protein kinase C inhibitor activity)
Seq-ID: ENSMUSP00000050374 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein domain specific binding regulation of cyclin-dependent protein kinase activity,
keratinocyte differentiation,
negative regulation of cell proliferation,
keratinocyte proliferation,
skin development
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 19 KAKLAEQAERYEDMAAFMKSA - 15286034
LTP
1.00
 - COIL
0.34
 - low
S 28 RYEDMAAFMKSAVEKGEELSC - 15286034
LTP
0.30
 - COIL
0.38
 - low
S 63 GGQRAAWRVLSSIEQKSNEEG - 15648052
HTP
1.00
 - 14_3_3
0.44
 - low
S 69 WRVLSSIEQKSNEEGSEEKGP - 15286034
LTP
0.14
 - 14_3_3
0.60
 - low
S 74 SIEQKSNEEGSEEKGPEVKEY - 15286034
LTP
0.06
 - 14_3_3
0.73
 - low
T 90 EVKEYREKVETELRGVCDTVL - 15286034
LTP
0.31
 - 14_3_3
0.33
 - low
T 98 VETELRGVCDTVLGLLDSHLI - 15286034
LTP
0.07
 - 14_3_3
0.22
 - low
S 116 HLIKGAGDAESRVFYLKMKGD - 15286034
LTP
0.96
 - 14_3_3
0.20
 - low
S 216 HTLSEDSYKDSTLIMQLLRDN - 15648052
HTP
0.99
 - 14_3_3
0.31
 - low

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