Substrate: SRF (Serum response factor)
Seq-ID: P11831 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-15523   MYOD1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein homodimerization activity,
specific RNA polymerase II transcription factor activity,
transcription factor binding,
sequence-specific DNA binding transcription factor activity,
serum response element binding		 cytoplasm,
nucleus		 senescence,
transcription,
positive regulation of cell differentiation,
neuron development,
regulation of smooth muscle cell differentiation,
response to hormone stimulus,
response to toxin,
positive regulation of transcription via serum response element binding,
response to cytokine stimulus,
heart looping,
positive regulation of smooth muscle contraction,
cell migration involved in sprouting angiogenesis,
muscle cell homeostasis,
trophectodermal cell differentiation,
angiogenesis involved in wound healing,
positive regulation of transcription initiation from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 77 TPAPTAGALYSGSEGDSESGE - 1547771
LTP
0.53
 MOD_CK2_1
 - -
0.81
 --
S 77 TPAPTAGALYSGSEGDSESGE CK2_alpha 2046671
LTP
0.53
 MOD_CK2_1
 - -
0.81
 --
S 77 TPAPTAGALYSGSEGDSESGE - 18669648
HTP
0.53
 MOD_CK2_1
 - -
0.81
 --
S 79 APTAGALYSGSEGDSESGEEE - 1547771
LTP
0.46
 MOD_CK2_1
 - -
0.79
 --
S 79 APTAGALYSGSEGDSESGEEE CK2_alpha 2046671
LTP
0.46
 MOD_CK2_1
 - -
0.79
 --
S 79 APTAGALYSGSEGDSESGEEE - 18669648
HTP
0.46
 MOD_CK2_1
 - -
0.79
 --
S 83 GALYSGSEGDSESGEEEELGA - 1547771
LTP
0.67
 MOD_CK2_1
 - -
0.77
 --
S 83 GALYSGSEGDSESGEEEELGA CK2_alpha 2046671
LTP
0.67
 MOD_CK2_1
 - -
0.77
 --
S 83 GALYSGSEGDSESGEEEELGA - 18669648
HTP
0.67
 MOD_CK2_1
 - -
0.77
 --
S 85 LYSGSEGDSESGEEEELGAER - 1547771
LTP
0.31
 - -
0.79
 --
S 85 LYSGSEGDSESGEEEELGAER MAPKAPK2 10318869
LTP
0.31
 - -
0.79
 --
S 85 LYSGSEGDSESGEEEELGAER - 11859076
LTP
0.31
 - -
0.79
 --
S 85 LYSGSEGDSESGEEEELGAER - 18669648
HTP
0.31
 - -
0.79
 --
S 103 AERRGLKRSLSEMEIGMVVGG RSK_group 8413226
LTP
0.91
 - -
0.53
 --
T 159 EFIDNKLRRYTTFSKRKTGIM PKC_alpha 12809504
LTP
0.74
 - MADS
0.38
 1K6O 50.68%
T 159 EFIDNKLRRYTTFSKRKTGIM DMPK_group 12809504
LTP
0.74
 - MADS
0.38
 1K6O 50.68%
S 224 LIQTCLNSPDSPPRSDPTTDQ - 17081983
HTP
0.31
 - -
0.80
 --
S 224 LIQTCLNSPDSPPRSDPTTDQ - 18669648
HTP
0.31
 - -
0.80
 --
S 228 CLNSPDSPPRSDPTTDQRMSA - 18669648
HTP
0.45
 - -
0.87
 --
S 435 DGSLTVLNAFSQAPSTMQVSH DNA-PK 8407951
LTP
0.23
 MOD_PIKK_1
 - -
0.46
 --
S 446 QAPSTMQVSHSQVQEPGGVPQ DNA-PK 8407951
LTP
0.00
 MOD_PIKK_1
 - -
0.68
 --

Substrate: SRF (Serum response factor)
Seq-ID: Q9JM73 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding transcription factor activity cytoplasm,
nucleus		 mesoderm formation,
transcription,
patterning of blood vessels,
positive regulation of filopodium assembly,
actin filament organization,
heart looping,
cell migration involved in sprouting angiogenesis,
muscle cell homeostasis,
developmental growth,
regulation of cell adhesion,
primitive streak formation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 99 AERRGLKRSLSEMELGVVVGG - 8413226
LTP
0.90
 - -
0.49
 --
S 220 LIQTCLNSPDSPPRSDPTTDQ - 17242355
HTP
0.29
 - -
0.80
 --

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