Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Spry-2 (Adaptor molecule)

Seq-ID:

O43597 [Homo sapiens]

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Interaction Network(s):

STRING

External Source(s):

Phosida

MINT Interaction(s):

[show]

MINT-6169734   GRB2_HUMAN
MINT-6170603   SH3K1_HUMAN
MINT-6539601   CBL_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	plasma membrane, cytosol, microtubule	signal transduction, cell-cell signaling

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	55	QIRAIRNTNEYTEGPTVVPRP	-	15637081	LTP	1.00		CBL SH2	-	0.81	-	medium
Y	55	QIRAIRNTNEYTEGPTVVPRP	-	16000370	LTP	1.00		CBL SH2	-	0.81	-	medium
Y	55	QIRAIRNTNEYTEGPTVVPRP	-	12593795	LTP	1.00		CBL SH2	-	0.81	-	medium
Y	55	QIRAIRNTNEYTEGPTVVPRP	SRC	15564375	LTP	1.00		CBL SH2	-	0.81	-	medium
Y	55	QIRAIRNTNEYTEGPTVVPRP	-	12815057	LTP	1.00		CBL SH2	-	0.81	-	medium
T	75	PGLKPAPRPSTQHKHERLHGL	DYRK1A	18678649	LTP	0.36		-	-	0.95	-	medium
Y	227	TCVCCVKGLFYHCSNDDEDNC	-	15637081	LTP	1.00		-	Sprouty	0.00	-	medium

Spry-2 (Adaptor molecule)

Seq-ID:

Q9QXV8 [Mus musculus]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

MINT Interaction(s):

MINT-19733 PLCG2_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	plasma membrane, cytoplasm, microtubule	branching morphogenesis of a tube, lung morphogenesis, negative regulation of Ras protein signal transduction, negative regulation of MAP kinase activity, negative regulation of cell proliferation, negative regulation of fibroblast growth factor receptor signaling pathway, negative regulation of nerve growth factor receptor signaling pathway, cell fate commitment, sensory perception of sound, negative regulation of Ras GTPase activity, inner ear morphogenesis, negative regulation of ERK1 and ERK2 cascade, lung growth

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	55	QIRAIRNTNEYTEGPTVVPRP	-	12402043	LTP	1.00		-	-	0.81	-	low