Substrate: TCF1 (protein binding, RNA polymerase II transcription factor acti...)
Seq-ID: P20823 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein heterodimerization activity,
protein homodimerization activity,
promoter binding,
sequence-specific DNA binding transcription factor activity		 cytoplasm,
nucleus		 regulation of gene-specific transcription from RNA polymerase II promoter,
glucose homeostasis,
positive regulation of transcription, DNA-dependent,
insulin secretion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 249 AECIQRGVSPSQAQGLGSNLV DYRK1B 11980910
LTP
1.00
 - HOX
0.57
 1IC8 59.84%

Substrate: TCF1 (protein binding, RNA polymerase II transcription factor acti...)
Seq-ID: P22361 [Mus musculus]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein heterodimerization activity,
protein homodimerization activity,
transcription activator activity,
promoter binding,
sequence-specific DNA binding transcription factor activity		 cytoplasm,
transcription factor complex,
photoreceptor outer segment,
pronucleus		 bile acid and bile salt transport,
regulation of Wnt receptor signaling pathway,
glucose homeostasis,
endocrine pancreas development,
response to oxidative stress,
heme biosynthetic process,
bile acid biosynthetic process,
fatty acid biosynthetic process,
placenta development,
blastocyst development,
response to glucose stimulus,
SMAD protein signal transduction,
paraxial mesoderm formation,
chromatin remodeling,
bone resorption,
fatty acid transport,
liver development,
regulation of insulin secretion,
insulin secretion,
reverse cholesterol transport,
embryonic limb morphogenesis,
positive regulation of transcription from RNA polymerase II promoter,
cholesterol metabolic process,
reproductive structure development,
protein localization
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 74 LGETRGSEDDTDDDGEDFAPP - 17203969
HTP
0.16
 - HNF-1_N
0.88
 - medium

Valid HTML 4.01 Transitional