Substrate: TNFRSF10A (caspase activator activity)
Seq-ID: O00220 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-15426   FADD_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
TRAIL binding,
transcription factor binding,
caspase activator activity,
death receptor activity		 integral to membrane activation of NF-kappaB-inducing kinase activity,
activation of caspase activity,
induction of apoptosis via death domain receptors
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 83 APGPRPAREASPRLRVHKTFK - 17081983
HTP
0.00
 - -
0.69
 - medium
T 461 SGKFIYLEDGTGSAVSLE    - 17081983
HTP
0.00
 - -
0.16
 - medium
S 463 KFIYLEDGTGSAVSLE      - 17081983
HTP
1.00
 - -
0.18
 - medium
S 466 YLEDGTGSAVSLE         - 17081983
HTP
0.00
 - -
0.23
 - medium

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